Wells' syndrome associated with churg-strauss syndrome

Soo Hyun Lee, Mi Ryung Roh, Hyunjoong Jee, Kee Yang Chung, Jin Young Jung

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Churg-Strauss syndrome (CSS) is a multisystem granulomatous vasculitis that is characterized by peripheral eosinophilia and the infiltration of eosinophils into systemic organs. The skin lesions of CSS consist mainly of palpable purpura and nodules. Wells' syndrome (WS) is a rare inflammatory dermatosis that is associated with recurrent granulomatous dermatitis and eosinophilia. Since these two diseases are rare, any overlap between them is very unusual. Herein, we report a patient with CSS, who initially presented a skin eruption of erythematous urticarial-plaques, vesicles, and blisters. Upon biopsy, the histology of these plaques indicated eosinophilic infiltration and "flame figures" within the dermis, which was consistent with a diagnosis of WS. Although the association between WS and CSS that was observed in our patient may be purely coincidental, it could also suggest a common pathogenetic background of these two distinct diseases, as both share several many common features.

Original languageEnglish
Pages (from-to)497-500
Number of pages4
JournalAnnals of Dermatology
Issue number4
Publication statusPublished - 2011 Nov

All Science Journal Classification (ASJC) codes

  • Dermatology


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