Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

Ju Yeong Kim; Tai Soon Yong; Han Jong Rim; Jong Yil Chai; Duk Young Min; Keeseon S. Eom; Woon Mok Sohn; Jae Hoon Lim; Dongil Choi; Sithat Insisiengmay; Bounlay Phommasack; Bounnaloth Insisiengmay

doi:10.1016/j.actatropica.2018.02.031

Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

Ju Yeong Kim, Tai Soon Yong, Han Jong Rim, Jong Yil Chai, Duk Young Min, Keeseon S. Eom, Woon Mok Sohn, Jae Hoon Lim, Dongil Choi, Sithat Insisiengmay, Bounlay Phommasack, Bounnaloth Insisiengmay

Department of Environmental Medical Biology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade ≥ 2) was also significantly more prevalent (P < 0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.

Original language	English
Pages (from-to)	128-134
Number of pages	7
Journal	Acta Tropica
Volume	182
DOIs	https://doi.org/10.1016/j.actatropica.2018.02.031
Publication status	Published - 2018 Jun

Bibliographical note

Funding Information:
Funding: This work was implemented through a Korea-Lao PDR Collaborative Project for Control of Foodborne Trematode Infections [2007–2011], which was supported by the Korea Foundation for International Healthcare (KOFIH) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science, and Technology [ 2011-0012166 ].

Publisher Copyright:
© 2018

All Science Journal Classification (ASJC) codes

Parasitology
veterinary (miscalleneous)
Insect Science
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.actatropica.2018.02.031

Cite this

@article{f292518e827c4aae85102615d5532e15,

title = "Ultrasonographic investigation of cholangiocarcinoma in Lao PDR",

abstract = "Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade ≥ 2) was also significantly more prevalent (P < 0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.",

author = "Kim, {Ju Yeong} and Yong, {Tai Soon} and Rim, {Han Jong} and Chai, {Jong Yil} and Min, {Duk Young} and Eom, {Keeseon S.} and Sohn, {Woon Mok} and Lim, {Jae Hoon} and Dongil Choi and Sithat Insisiengmay and Bounlay Phommasack and Bounnaloth Insisiengmay",

note = "Funding Information: Funding: This work was implemented through a Korea-Lao PDR Collaborative Project for Control of Foodborne Trematode Infections [2007–2011], which was supported by the Korea Foundation for International Healthcare (KOFIH) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science, and Technology [ 2011-0012166 ]. Publisher Copyright: {\textcopyright} 2018",

year = "2018",

month = jun,

doi = "10.1016/j.actatropica.2018.02.031",

language = "English",

volume = "182",

pages = "128--134",

journal = "Acta Tropica",

issn = "0001-706X",

publisher = "Elsevier",

}

TY - JOUR

T1 - Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

AU - Kim, Ju Yeong

AU - Yong, Tai Soon

AU - Rim, Han Jong

AU - Chai, Jong Yil

AU - Min, Duk Young

AU - Eom, Keeseon S.

AU - Sohn, Woon Mok

AU - Lim, Jae Hoon

AU - Choi, Dongil

AU - Insisiengmay, Sithat

AU - Phommasack, Bounlay

AU - Insisiengmay, Bounnaloth

N1 - Funding Information: Funding: This work was implemented through a Korea-Lao PDR Collaborative Project for Control of Foodborne Trematode Infections [2007–2011], which was supported by the Korea Foundation for International Healthcare (KOFIH) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science, and Technology [ 2011-0012166 ]. Publisher Copyright: © 2018

PY - 2018/6

Y1 - 2018/6

N2 - Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade ≥ 2) was also significantly more prevalent (P < 0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.

AB - Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade ≥ 2) was also significantly more prevalent (P < 0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.

UR - http://www.scopus.com/inward/record.url?scp=85042657039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85042657039&partnerID=8YFLogxK

U2 - 10.1016/j.actatropica.2018.02.031

DO - 10.1016/j.actatropica.2018.02.031

M3 - Article

C2 - 29486176

AN - SCOPUS:85042657039

SN - 0001-706X

VL - 182

SP - 128

EP - 134

JO - Acta Tropica

JF - Acta Tropica

ER -

Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this