Two-dimensional materials in biomedical, biosensing and sensing applications

Nasuha Rohaizad, Carmen C. Mayorga-Martinez, Michaela Fojtů, Naziah M. Latiff, Martin Pumera

Research output: Contribution to journalReview articlepeer-review

223 Citations (Scopus)


Two-dimensional (2D) materials are at the forefront of materials research. Here we overview their applications beyond graphene, such as transition metal dichalcogenides, monoelemental Xenes (including phosphorene and bismuthene), carbon nitrides, boron nitrides along with transition metal carbides and nitrides (MXenes). We discuss their usage in various biomedical and environmental monitoring applications, from biosensors to therapeutic treatment agents, their toxicity and their utility in chemical sensing. We highlight how a specific chemical, physical and optical property of 2D materials can influence the performance of bio/sensing, improve drug delivery and photo/thermal therapy as well as affect their toxicity. Such properties are determined by crystal phases electrical conductivity, degree of exfoliation, surface functionalization, strong photoluminescence, strong optical absorption in the near-infrared range and high photothermal conversion efficiency. This review conveys the great future of all the families of 2D materials, especially with the expanding 2D materials' landscape as new materials emerge such as germanene and silicene.

Original languageEnglish
Pages (from-to)619-657
Number of pages39
JournalChemical Society reviews
Issue number1
Publication statusPublished - 2021 Jan 7

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)


Dive into the research topics of 'Two-dimensional materials in biomedical, biosensing and sensing applications'. Together they form a unique fingerprint.

Cite this