Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease

Hayoung Choi; Byung Woo Jhun; Su Young Kim; Dae Hun Kim; Hyun Lee; Kyeongman Jeon; O. Jung Kwon; Hee Jae Huh; Chang Seok Ki; Nam Yong Lee; Sung Jae Shin; Charles L. Daley; Won Jung Koh

doi:10.1016/j.diagmicrobio.2017.12.008

Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease

Hayoung Choi, Byung Woo Jhun, Su Young Kim, Dae Hun Kim, Hyun Lee, Kyeongman Jeon, O. Jung Kwon, Hee Jae Huh, Chang Seok Ki, Nam Yong Lee, Sung Jae Shin, Charles L. Daley, Won Jung Koh

Department of Microbiology

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%–20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.

Original language	English
Pages (from-to)	293-295
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	90
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2017.12.008
Publication status	Published - 2018 Apr

Bibliographical note

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning ( NRF-2015R1A2A1A01003959 ) and the Ministry of Education ( NRF-2016R1A6A3A11930364 ).

Publisher Copyright:
© 2017 Elsevier Inc.

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diagmicrobio.2017.12.008

Cite this

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title = "Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease",

abstract = "Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%–20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.",

author = "Hayoung Choi and Jhun, {Byung Woo} and Kim, {Su Young} and Kim, {Dae Hun} and Hyun Lee and Kyeongman Jeon and Kwon, {O. Jung} and Huh, {Hee Jae} and Ki, {Chang Seok} and Lee, {Nam Yong} and Shin, {Sung Jae} and Daley, {Charles L.} and Koh, {Won Jung}",

note = "Funding Information: This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning ( NRF-2015R1A2A1A01003959 ) and the Ministry of Education ( NRF-2016R1A6A3A11930364 ). Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2018",

month = apr,

doi = "10.1016/j.diagmicrobio.2017.12.008",

language = "English",

volume = "90",

pages = "293--295",

journal = "Diagnostic Microbiology and Infectious Disease",

issn = "0732-8893",

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AU - Choi, Hayoung

AU - Jhun, Byung Woo

AU - Kim, Su Young

AU - Kim, Dae Hun

AU - Lee, Hyun

AU - Jeon, Kyeongman

AU - Kwon, O. Jung

AU - Huh, Hee Jae

AU - Ki, Chang Seok

AU - Lee, Nam Yong

AU - Shin, Sung Jae

AU - Daley, Charles L.

AU - Koh, Won Jung

N1 - Funding Information: This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning ( NRF-2015R1A2A1A01003959 ) and the Ministry of Education ( NRF-2016R1A6A3A11930364 ). Publisher Copyright: © 2017 Elsevier Inc.

PY - 2018/4

Y1 - 2018/4

N2 - Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%–20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.

AB - Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15%–20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.

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DO - 10.1016/j.diagmicrobio.2017.12.008

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ER -

Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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