TY - JOUR
T1 - Total chemical synthesis and X-ray crystal structure of a protein diastereomer
T2 - [D-Gln35]ubiquitin
AU - Bang, Duhee
AU - Makhatadze, George I.
AU - Tereshko, Valentina
AU - Kossiakoff, Anthony A.
AU - Kent, Stephen B.
PY - 2005/6/20
Y1 - 2005/6/20
N2 - (Figure Presented) Striking similarity: An efficient synthetic route to native ubiquitin and its diastereomer [D-Gln35]ubiquitin was realized by combining a one-pot native chemical ligation process with protein desulfurization. High-resolution X-ray crystallographic studies of the protein diastereomer (see picture) revealed a striking conservation of molecular structure.
AB - (Figure Presented) Striking similarity: An efficient synthetic route to native ubiquitin and its diastereomer [D-Gln35]ubiquitin was realized by combining a one-pot native chemical ligation process with protein desulfurization. High-resolution X-ray crystallographic studies of the protein diastereomer (see picture) revealed a striking conservation of molecular structure.
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U2 - 10.1002/anie.200463040
DO - 10.1002/anie.200463040
M3 - Article
C2 - 15834850
AN - SCOPUS:21244494055
SN - 1433-7851
VL - 44
SP - 3852
EP - 3856
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 25
ER -