Topographic anatomy of the infraorbital artery and its clinical implications for nasolabial fold augmentation

Hong San Kim, Kyu Lim Lee, Young Chun Gil, Kyung Seok Hu, Tanvaa Tansatit, Hee Jin Kim

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Background: Understanding the topography of the blood vessels distributed around the nasolabial fold region is essential for ensuring the safety of dermal filler injections into the nasolabial fold. The purpose of this study was to provide anatomical information on the infraorbital artery distribution and its relationship with the facial artery for use in clinical procedures involving filler injection during nasolabial fold augmentation. Methods: The infraorbital artery was investigated in the nasolabial fold region divided into zones I to XII based on clock-hour meridians centered on the infraorbital foramen. The running layers of the infraorbital artery and infraorbital nerve were also compared in the infraorbital foramen. Changes in the infraorbital artery were observed according to vascular dominance of the facial artery. Results: The infraorbital artery was divided into three main branches, palpebral, nasal, and labial infraorbital artery branches in 34.7, 100, and 100 percent of the specimens, respectively; with these branches of palpebral, nasal, and labial infraorbital artery observed most commonly in zones I, V, and VI, respectively. Analysis of the bilateral facial artery topography revealed that its vascular dominance was observed in 19.4 percent. The infraorbital artery was thicker and had a wider distribution on the nondominant side of the facial artery, whereas the nasal infraorbital nerve anastomosed with the facial artery in the lateral nasal region in 57.1 percent. Conclusion: Investigating and verifying the vascular structure regarding its interactions with the facial artery and infraorbital artery will provide critical information to physicians performing facial surgery and cosmetic procedures.

Original languageEnglish
Pages (from-to)273E-280E
JournalPlastic and reconstructive surgery
Issue number3
Publication statusPublished - 2018 Sept

Bibliographical note

Funding Information:
This work was supported by a National Research Foundation of Korea grant funded by the Korean government (Ministry of Science, ICT, and Future Planning) (NRF-2017R1A2B4003781). The authors would like to thank the cadaver donors and their families for participating in the donation program. The authors thank Alex Lim from New York University and Hayoung Yoo from the University of California, Berkeley for revising the manuscript.

Publisher Copyright:
Copyright © 2018 by the American Society of Plastic Surgeons.

All Science Journal Classification (ASJC) codes

  • Surgery


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