Titanium surface modification by using microwave-induced argon plasma in various conditions to enhance osteoblast biocompatibility

Gyeung Mi Seon, Hyok Jin Seo, Soon Young Kwon, Mi Hee Lee, Byeong Ju Kwon, Min Sung Kim, Min Ah Koo, Bong Joo Park, Jong Chul Park

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


Background: Titanium is a well proven implantable material especially for osseointegratable implants by its biocompatibility and anti-corrosive surface properties. Surface characteristics of the implant play an important role for the evolution of bone tissue of the recipient site. Among the various surface modification methods, plasma treatment is one of the promising methods for enhance biocompatibility. We made microwave-induced argon plasma at atmospheric pressure to improve in titanium surface biocompatibility. Results: Various states of emission spectra from excited species-argon, nitrogen atoms and oxygen atoms were observed. The electron energy band structures are the unique characteristics of atoms and functional groups. Microwaveinduced argon plasma treatment changed the titanium surface to be very hydrophilic especially on the 5 s short treatment and 30 s, 90 s long treatment samples that detected by contact angle measurement. MC3T3-E1 attachment and proliferation assay significantly increased in 5 s at short treatment, 30 s, and 90 s at long treatment after 5 days incubation. Conclusions: Result indicated that microwave-induce argon plasma treatment would be an effective method to modify titanium surface for enhancing cell-material interactions.

Original languageEnglish
Article number13
JournalBiomaterials Research
Issue number1
Publication statusPublished - 2015

Bibliographical note

Publisher Copyright:
© 2015 Seon et al.

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering


Dive into the research topics of 'Titanium surface modification by using microwave-induced argon plasma in various conditions to enhance osteoblast biocompatibility'. Together they form a unique fingerprint.

Cite this