The use of a light-emitting diode device for neck rejuvenation and its safety on thyroid glands

Young In Lee, Eunjung Lee, Kee Hyun Nam, Dong Yeob Shin, Jihee Kim, Jangmi Suk, Jin Young Kwak, Ju Hee Lee

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Home-use light-emitting diodes (LEDs) are attracting growing attention regarding their anti-aging effects. Although most previous studies on the use of LED devices as a form of low-level laser therapy reported no significant adverse events, questions regarding the safety of using a light source on secretory tissues have been raised. This study aimed to assess the safety and efficacy of a home-use LED device for neck skin rejuvenation, particularly regarding its effect on thyroid gland morphology and function. Thyroid function tests and ultrasonographic analyses showed no significant changes after 16 weeks of LED use. Evaluation using the Lemperle wrinkle scale and global improvement scales by both investigators and subjects showed significant improvement after 16 weeks of daily application, as well as 8 weeks after discontinuation. Biophysical parameters, such as hydration, elasticity, and density, also showed significant improvements. Hence, the long-term use of the LED device was safe and effective for neck rejuvenation, and showed no significant side effects on the adjacent thyroid and parathyroid glands.

Original languageEnglish
Article number1774
JournalJournal of Clinical Medicine
Issue number8
Publication statusPublished - 2021 Apr 2

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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