The role of angiogenesis and pulpal healing in tooth replantation and allograft transplantation

Dong Joon Lee, Seung Jun Lee, Min Jung Lee, Eun Jung Kim, Hayato Ohshima, Han Sung Jung

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Tooth transplantation is one of the treatment options for extracted teeth that can be considered before dental implantation. Although the success rate of tooth transplantation is lower than that of implantation, tooth replantation and transplantation have the great advantage of using natural teeth. Tooth replantation might be considered a promising option in some cases. In present study, the expression patterns of revascularization and pulpal healing, which are the most important for the pulp viability, were analyzed after tooth replantation and allograft in mice. The inflammatory response and root dentin resorption were observed and not different between replantation and allograft in initiation of healing process. However, bonelike tissue formation, pulp revascularization and pulp healing were faster in replantation. The difference of healing patterns between tooth replantation and allograft found in present study will be helpful to select the treatment option and to understand healing mechanism.

Original languageEnglish
Article number100945
JournalBiochemistry and Biophysics Reports
Publication statusPublished - 2021 Jul

Bibliographical note

Publisher Copyright:
© 2021 The Authors

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry


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