The potential use of a ketogenic diet in pancreatobiliary cancer patients after pancreatectomy

Ju Hye Ok, Hosun Lee, Hae Yun Chung, Sung Hwan Lee, Eun Jeong Choi, Chang Moo Kang, Song Mi Lee

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Background/Aim: High-carbohydrate diets are generally provided to post-pancreatectomy cancer patients. Low energy density of this diet may obstruct proper energy intake and recovery. This study aimed to assess the effects of high-fat, high-energy ketogenic diet (KD) in these patients. Patients and Methods: After pancreatectomy, 9 patients were provided with general diet (GD) while 10 were served KD. Meal compliance, energy intake rate, meal satisfaction and presence of complications were monitored throughout hospital stay. Data on nutritional status, serum lipids and body composition were collected and compared between groups. Results: Meal compliance, energy intake rate and meal satisfaction score were higher in KD. There were no differences in complications, nutritional status and serum lipids. The decrease in body cell mass (BCM) was greater in GD. Conclusion: Postpancreatectomy cancer patients who consumed KD had a higher energy intake and BCM. These results suggest the potential use of KD as an adjuvant anti-cancer therapy.

Original languageEnglish
Pages (from-to)6519-6527
Number of pages9
JournalAnticancer research
Issue number11
Publication statusPublished - 2018 Nov

Bibliographical note

Funding Information:
This work was supported by Korea Evaluation for Technology in Food, Fisheries (iPET, 316055-3).

Publisher Copyright:
© 2018 International Institute of Anticancer Research.All right reserved.

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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