TY - JOUR
T1 - The optimal endoscopic screening interval for detecting early gastric neoplasms
AU - Park, Chan Hyuk
AU - Kim, Eun Hye
AU - Chung, Hyunsoo
AU - Lee, Hyuk
AU - Park, Jun Chul
AU - Shin, Sung Kwan
AU - Lee, Yong Chan
AU - An, Ji Yeong
AU - Kim, Hyoung Il
AU - Cheong, Jae Ho
AU - Hyung, Woo Jin
AU - Noh, Sung Hoon
AU - Kim, Choong Bae
AU - Lee, Sang Kil
PY - 2014/8
Y1 - 2014/8
N2 - Background The optimal interval between endoscopic examinations for detecting early gastric neoplasms, including gastric adenomas, has not previously been studied. Objective To clarify the optimal interval between endoscopic examinations for the early diagnosis of both gastric cancers and adenomas. Design Retrospective study. Setting University-affiliated tertiary-care hospital, Seoul, Korea. Patients Patients who were treated for gastric neoplasms between January 2008 and August 2013. Interventions Questionnaire survey for interval between the penultimate endoscopy and diagnosis of a gastric neoplasm. A total of 846 patients were divided into 5 groups according to the interval between endoscopic examinations. Main Outcome Measurements The proportion of gastric neoplasms treated with endoscopic submucosal dissection and the proportion of advanced gastric cancers according to the interval between endoscopic examinations. Results In total, 197, 430, and 219 patients were diagnosed with gastric adenoma, early gastric cancer, and advanced gastric cancer, respectively. In multivariate analysis, the proportion of gastric neoplasms treated with endoscopic submucosal dissection was significantly higher in the ≤12 months, 12 to 24 months, and 24 to 36 months endoscopy interval groups than in the no endoscopy within 5 years group (all P <.001). In addition, the proportion of advanced gastric cancers was significantly lower in the ≤12 months and 12 to 24 months endoscopy interval groups than in the no endoscopy within 5 years group (all P <.001). Limitations Retrospective study and recall bias. Conclusion Annual endoscopy cannot facilitate the detection of endoscopically treatable gastric neoplasms compared with biennial or triennial endoscopy. We recommend biennial endoscopic screening for gastric neoplasms in order to increase the proportion of lesions discovered while they are still endoscopically treatable and to reduce the number of lesions that progress to advanced gastric cancer.
AB - Background The optimal interval between endoscopic examinations for detecting early gastric neoplasms, including gastric adenomas, has not previously been studied. Objective To clarify the optimal interval between endoscopic examinations for the early diagnosis of both gastric cancers and adenomas. Design Retrospective study. Setting University-affiliated tertiary-care hospital, Seoul, Korea. Patients Patients who were treated for gastric neoplasms between January 2008 and August 2013. Interventions Questionnaire survey for interval between the penultimate endoscopy and diagnosis of a gastric neoplasm. A total of 846 patients were divided into 5 groups according to the interval between endoscopic examinations. Main Outcome Measurements The proportion of gastric neoplasms treated with endoscopic submucosal dissection and the proportion of advanced gastric cancers according to the interval between endoscopic examinations. Results In total, 197, 430, and 219 patients were diagnosed with gastric adenoma, early gastric cancer, and advanced gastric cancer, respectively. In multivariate analysis, the proportion of gastric neoplasms treated with endoscopic submucosal dissection was significantly higher in the ≤12 months, 12 to 24 months, and 24 to 36 months endoscopy interval groups than in the no endoscopy within 5 years group (all P <.001). In addition, the proportion of advanced gastric cancers was significantly lower in the ≤12 months and 12 to 24 months endoscopy interval groups than in the no endoscopy within 5 years group (all P <.001). Limitations Retrospective study and recall bias. Conclusion Annual endoscopy cannot facilitate the detection of endoscopically treatable gastric neoplasms compared with biennial or triennial endoscopy. We recommend biennial endoscopic screening for gastric neoplasms in order to increase the proportion of lesions discovered while they are still endoscopically treatable and to reduce the number of lesions that progress to advanced gastric cancer.
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U2 - 10.1016/j.gie.2014.01.030
DO - 10.1016/j.gie.2014.01.030
M3 - Article
C2 - 24613579
AN - SCOPUS:84904761068
SN - 0016-5107
VL - 80
SP - 253
EP - 259
JO - Gastrointestinal endoscopy
JF - Gastrointestinal endoscopy
IS - 2
ER -
