TY - JOUR
T1 - The clinical features and optimal treatment of anorectal malignant melanoma
AU - Nam, Soomin
AU - Kim, Chang Woo
AU - Baek, Se Jin
AU - Hur, Hyuk
AU - Min, Byung Soh
AU - Baik, Seung Hyuk
AU - Kim, Nam Kyu
N1 - Publisher Copyright:
©2014, the Korean Surgical Society.
PY - 2014/9/1
Y1 - 2014/9/1
N2 - Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.
AB - Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.
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U2 - 10.4174/astr.2014.87.3.113
DO - 10.4174/astr.2014.87.3.113
M3 - Article
AN - SCOPUS:84986626312
SN - 2288-6575
VL - 87
SP - 113
EP - 117
JO - Annals of Surgical Treatment and Research
JF - Annals of Surgical Treatment and Research
IS - 3
ER -
