The clinical effects of calcium sulfate combined with calcium carbonate in intrabony defects

Bone grafts using calcium carbonate (CC) and guided tissue regeneration (GTR) using calcium sulfate (CS) will maximize their advantages and show the best clinical results in intrabony defects. The purpose of this study was to compare the effects of a combination of CS and CC with control treated only with modified widman flap in a periodontal repair of intrabony defects. As many as 30 patients at Yonsei University Hospital were enrolled in this study. Of this group, 10 patients were treated with a combination of CS and CC as the experimental group α another 10 were treated with CC as the experimental group β, and the remaining 10 patients, the control group, were treated only with modified widman flap. The results are follows: (i) The probing depth changes were significantly different (P < 0.05) between the control and experimental group. However, there were no significant differences (P < 0.05) between the experimental group β and α. (ii) The gingival recession changes were not significantly different (P < 0.05) among the groups, (iii) The attachment level changes were significantly different (P < 0.05) between the control and experimental group. However, there were no significant differences (P < 0.05) between the experimental group β and α. (iv) The bone probing depth changes were significantly different (P < 0.05) among the groups. On the basis of these results, it would be concluded that treatment using a combination of CS and CC had the potential to improve periodontal parameters in human intrabony defects.