Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Young Bin Ji; Sang Hoon Kim; Kiyoung Jeong; Yuna Choi; Joo Hiuk Son; Dong Woo Park; Sam Kyu Noh; Tae In Jeon; Yong Min Huh; Seungjoo Haam; Sang Kil Lee; Seung Jae Oh; Jin Suck Suh

doi:10.1364/BOE.5.004162

Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Young Bin Ji, Sang Hoon Kim, Kiyoung Jeong, Yuna Choi, Joo Hiuk Son, Dong Woo Park, Sam Kyu Noh, Tae In Jeon, Yong Min Huh, Seungjoo Haam, Sang Kil Lee, Seung Jae Oh, Jin Suck Suh

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

Original language	English
Article number	A4162
Pages (from-to)	4162-4170
Number of pages	9
Journal	Biomedical Optics Express
Volume	5
Issue number	12
DOIs	https://doi.org/10.1364/BOE.5.004162
Publication status	Published - 2014

Bibliographical note

Publisher Copyright:
© 2014 Optical Society of America.

All Science Journal Classification (ASJC) codes

Biotechnology
Atomic and Molecular Physics, and Optics

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10.1364/BOE.5.004162

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title = "Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model",

abstract = "We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.",

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AU - Ji, Young Bin

AU - Kim, Sang Hoon

AU - Jeong, Kiyoung

AU - Choi, Yuna

AU - Son, Joo Hiuk

AU - Park, Dong Woo

AU - Noh, Sam Kyu

AU - Jeon, Tae In

AU - Huh, Yong Min

AU - Haam, Seungjoo

AU - Lee, Sang Kil

AU - Oh, Seung Jae

AU - Suh, Jin Suck

PY - 2014

Y1 - 2014

N2 - We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

AB - We have investigated basic properties of normal gastrointestinal (GI) tract tissues, including glandular stomach (GS), fore stomach (FS), large intestine (LI), small intestine (SI), and esophagus (ESO), from a rat model using terahertz (THz) reflection imaging and spectroscopy. The THz images collected from stratified squamous epithelia (SSE) of FS and ESO show a lower peak-to-peak value compared to those from columnar epithelia (CE) of GS, LI, or SI because the SSE contains less water than CE. The refractive index and absorption coefficient of FS were less than those of GS or LI, both having values similar to those of water. Additionally, we report internal reflection THz signals from ESO, although we were unable to determine the exact interface for this internal reflection.

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Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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