TAB-TICI Score: Successful Recanalization Score After Endovascular Thrombectomy in Acute Stroke

Woo Keun Seo, Hyo Suk Nam, Jong Won Chung, Young Dae Kim, Keon Ha Kim, Oh Young Bang, Byung Moon Kim, Gyeung Moon Kim, Pyoung Jeon, Ji Hoe Heo

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Background and Purpose: Successful reperfusion therapy is supposed to be comprehensive and validated beyond the grade of recanalization. This study aimed to develop a novel scoring system for defining the successful recanalization after endovascular thrombectomy. Methods: We analyzed the data of consecutive acute stroke patients who were eligible to undergo reperfusion therapy within 24 h of onset and who underwent mechanical thrombectomy using a nationwide multicenter stroke registry. A new score was produced using the predictors which were directly linked to the procedure to evaluate the performance of the thrombectomy procedure. Results: In total, 446 patients in the training population and 222 patients in the validation population were analyzed. From the potential components of the score, four items were selected: Emergency Room-to-puncture time (T), adjuvant devices used (A), procedural intracranial bleeding (B), and post-thrombectomy reperfusion status [Thrombolysis in Cerebral Infarction (TICI)]. Using these items, the TAB-TICI score was developed, which showed good performance in terms of discriminating early neurological aggravation [AUC 0.73, 95% confidence interval (CI) 0.67–0.78, P < 0.01] and favorable outcomes (AUC 0.69, 95% CI 0.64–0.75, P < 0.01) in the training population. The stability of the TAB-TICI score was confirmed by external validation and sensitivity analyses. The TAB-TICI score and its derived grade of successful recanalization were significantly associated with the volume of thrombectomy cases at each site and in each admission year. Conclusion: The TAB-TICI score is a valid and easy-to-use tool to more comprehensively define successful recanalization after endovascular thrombectomy in acute stroke patients with large vessel occlusion.

Original languageEnglish
Article number692490
JournalFrontiers in Neurology
Publication statusPublished - 2021 Oct 14

Bibliographical note

Publisher Copyright:
© Copyright © 2021 Seo, Nam, Chung, Kim, Kim, Bang, Kim, Kim, Jeon and Heo.

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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