Synthesis of new diselenide compounds as anti-inflammatory agents

Liulan Shen; Kyung Min Shin; Kyung Tae Lee; Jin Hyun Jeong

doi:10.1007/BF02980171

Synthesis of new diselenide compounds as anti-inflammatory agents

Liulan Shen, Kyung Min Shin, Kyung Tae Lee, Jin Hyun Jeong

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as antiinflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.

Original language	English
Pages (from-to)	816-819
Number of pages	4
Journal	Archives of pharmacal research
Volume	27
Issue number	8
DOIs	https://doi.org/10.1007/BF02980171
Publication status	Published - 2004 Aug 31

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery
Organic Chemistry

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10.1007/BF02980171

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abstract = "Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as antiinflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.",

author = "Liulan Shen and Shin, {Kyung Min} and Lee, {Kyung Tae} and Jeong, {Jin Hyun}",

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AU - Jeong, Jin Hyun

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AB - Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as antiinflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.

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Synthesis of new diselenide compounds as anti-inflammatory agents

Abstract

All Science Journal Classification (ASJC) codes

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