Synthesis of new C2-symmetric bioxazoles and application as chiral ligands in asymmetric hydrosilylation

Sang Gi Lee; Chung Woo Lim; Choong Eui Song; In O. Kim; Chul Ho Jun

doi:10.1016/S0957-4166(97)00353-4

Synthesis of new C₂-symmetric bioxazoles and application as chiral ligands in asymmetric hydrosilylation

Sang Gi Lee, Chung Woo Lim, Choong Eui Song, In O. Kim, Chul Ho Jun

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

New C₂-symmetric chiral (4S,4'S)-bioxazoles 3a and 3b, possessing chirality on their backbone, were synthesized efficiently starting from L-tartaric acid. The structure of 3a was determined by X-ray crystal structure analysis. With these novel chiral bioxazole ligands, as a preliminary investigation for their effects on the enantioselectivity, rhodium(I)-catalyzed enantioselective hydrosilylations of acetophenone were carried out.

Original language	English
Pages (from-to)	2927-2932
Number of pages	6
Journal	Tetrahedron Asymmetry
Volume	8
Issue number	17
DOIs	https://doi.org/10.1016/S0957-4166(97)00353-4
Publication status	Published - 1997 Sept 11

Bibliographical note

Funding Information:
This research was supported by grant from Ministry of Science and Technology like to thank Dr K. M. Kim for help with X-ray analysis.

All Science Journal Classification (ASJC) codes

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

Access to Document

10.1016/S0957-4166(97)00353-4

Cite this

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title = "Synthesis of new C2-symmetric bioxazoles and application as chiral ligands in asymmetric hydrosilylation",

abstract = "New C2-symmetric chiral (4S,4'S)-bioxazoles 3a and 3b, possessing chirality on their backbone, were synthesized efficiently starting from L-tartaric acid. The structure of 3a was determined by X-ray crystal structure analysis. With these novel chiral bioxazole ligands, as a preliminary investigation for their effects on the enantioselectivity, rhodium(I)-catalyzed enantioselective hydrosilylations of acetophenone were carried out.",

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AU - Lee, Sang Gi

AU - Lim, Chung Woo

AU - Song, Choong Eui

AU - Kim, In O.

AU - Jun, Chul Ho

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Y1 - 1997/9/11

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