Susceptibility of several strains of mice to Echinostoma hortense infection.

Kyu Jae Lee, Seung Kyu Park, Jee Aee Im, Soo Kie Kim, Geun Ha Kim, Gwang Young Kim, Eun Ju Yang, Yong Suk Ryang

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14 Citations (Scopus)


Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed from 1 to 8 weeks after infection with 30 metacercariae. C3H/HeN and ICR mice showed the highest worm maturation rates. The worm recovery rate and the number of eggs per gram (EPG) of feces was also higher in C3H/HeN and ICR mice than in BALB/c, C57BL6, and FvB mice. It is suggested that E. hortense is highly infectious to ICR and C3H/HeN mice, but not to the other strains of mice. Based on the results obtained, we believe that the susceptibility of different mouse strains to E. hortense infection is dependent on the genetic and immunologic background of mice.

Original languageEnglish
Pages (from-to)51-56
Number of pages6
JournalThe Korean journal of parasitology
Issue number2
Publication statusPublished - 2004 Jun

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases


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