Surgical treatment of two patients with infantile spasms in early infancy

Hoon Chul Kang, Da Eun Jung, Kae Min Kim, Yong Soon Hwang, Sang Keun Park, Tae Sung Ko

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Early surgery for catastrophic epilepsy may prevent developmental deterioration and minimize functional deficit resulting from the surgical procedure. We report two patients who had infantile spasms and underwent surgery for epilepsy in early infancy (younger than 6 months old). Magnetic resonance imaging showed cortical dysplasia in both patients. One patient underwent lesionectomy in the right perirolandic area at 49 weeks conceptional age (CA) and the other infant underwent left temporo-occipital disconnection at 45 weeks CA. Both showed Engel classification I and catch-up developmental progress. However, with the second patient, we were concerned about the high volume transfusion relative to her body weight during the extensive disconnection because of the patient's small blood volume. We discuss the benefits and potential risks of surgical treatment for intractable epilepsy in early infancy.

Original languageEnglish
Pages (from-to)453-457
Number of pages5
JournalBrain and Development
Issue number7
Publication statusPublished - 2006 Aug

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology


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