Surgical outcome and prognostic factors influencing visual acuity in myopic foveoschisis patients

Dong Hyun Lee, Inhee Moon, Hyun Goo Kang, Eun Young Choi, Sung Soo Kim, Suk Ho Byeon, Hyoung Jun Koh, Sung Chul Lee, Min Kim

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Background: To analyze the optical coherence tomography (OCT) characteristics and visual outcome of vitrectomy in myopic foveoschisis (MF) patients and identify prognostic factors. Methods: This study is a retrospective clinical cohort study in tertiary care hospital. Thirty-two eyes of 32 patients who underwent MF-related vitrectomy in were investigated retrospectively. Best-corrected visual acuity (BCVA) measured at 1 year post surgery and changes in central foveal thickness (CFT) and co-existing macular pathologies, such as foveal detachment (FD), lamellar holes, and macular holes were the main outcome measures. Prognostic factors were identified using multivariate linear regression analysis. Results: Average BCVA (in logarithm of the minimum angle of resolution) and mean CFT had improved from 0.46 ± 0.06 to 0.37 ± 0.07 (P = 0.089) and from 485.72 ± 164.69 to 341.71 ± 109.70 (P < 0.001), respectively. Univariate analysis identified baseline BCVA, epiretinal membrane, no coexisting OCT features other than MF, FD on OCT, and gas injection as significantly associated with visual outcome (P < 0.001, 0.014, 0.022, < 0.001, and 0.030). Better baseline BCVA and absence of FD on OCT remained significant (P < 0.001 and < 0.001, respectively) after multivariate analysis. Conclusion: Good preoperative visual acuity and absence of FD pre-surgery are important predictors of good visual prognosis. Thus, timely surgical intervention, before development of macular complications, may improve visual outcome after surgical treatment of patients with MF.

Original languageEnglish
Pages (from-to)1642-1648
Number of pages7
JournalEye (Basingstoke)
Issue number10
Publication statusPublished - 2019 Oct 1

Bibliographical note

Publisher Copyright:
© 2019, The Royal College of Ophthalmologists.

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems


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