Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe; Byeong Uk Jeon; Myoung Eun Jung; Moon Kook Jeon; Inji Shin; Byoung Chul Cho; Gildon Choi; Chong Hak Chae; Kwangho Lee

doi:10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

Hyeonjeong Choe, Byeong Uk Jeon, Myoung Eun Jung, Moon Kook Jeon, Inji Shin, Byoung Chul Cho, Gildon Choi, Chong Hak Chae, Kwangho Lee

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Original language	English
Pages (from-to)	1353-1357
Number of pages	5
Journal	Bulletin of the Korean Chemical Society
Volume	38
Issue number	11
DOIs	https://doi.org/10.1002/bkcs.11287
Publication status	Published - 2017 Nov

Bibliographical note

Funding Information:
The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01).

Funding Information:
Acknowledgments. The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01).

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1002/bkcs.11287

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Choe, H., Jeon, B. U., Jung, M. E., Jeon, M. K., Shin, I., Cho, B. C., Choi, G., Chae, C. H., & Lee, K. (2017). Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. Bulletin of the Korean Chemical Society, 38(11), 1353-1357. https://doi.org/10.1002/bkcs.11287

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title = "Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment",

author = "Hyeonjeong Choe and Jeon, {Byeong Uk} and Jung, {Myoung Eun} and Jeon, {Moon Kook} and Inji Shin and Cho, {Byoung Chul} and Gildon Choi and Chae, {Chong Hak} and Kwangho Lee",

note = "Funding Information: The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01). Funding Information: Acknowledgments. The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01).",

year = "2017",

month = nov,

doi = "10.1002/bkcs.11287",

language = "English",

volume = "38",

pages = "1353--1357",

journal = "Bulletin of the Korean Chemical Society",

issn = "0253-2964",

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}

Choe, H, Jeon, BU, Jung, ME, Jeon, MK, Shin, I, Cho, BC, Choi, G, Chae, CH & Lee, K 2017, 'Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment', Bulletin of the Korean Chemical Society, vol. 38, no. 11, pp. 1353-1357. https://doi.org/10.1002/bkcs.11287

Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment. / Choe, Hyeonjeong; Jeon, Byeong Uk; Jung, Myoung Eun et al.
In: Bulletin of the Korean Chemical Society, Vol. 38, No. 11, 11.2017, p. 1353-1357.

Research output: Contribution to journal › Article › peer-review

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AU - Choe, Hyeonjeong

AU - Jeon, Byeong Uk

AU - Jung, Myoung Eun

AU - Jeon, Moon Kook

AU - Shin, Inji

AU - Cho, Byoung Chul

AU - Choi, Gildon

AU - Chae, Chong Hak

AU - Lee, Kwangho

N1 - Funding Information: The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01). Funding Information: Acknowledgments. The authors greatly acknowledge the generous financial support from the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (NRF-2012M3A9C1053340, NRF-2016R1A2B3016282) and the Korea Research Institute of Chemical Technology (KK1703-B01).

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Structure–Activity Relationship Study of 2,4-Dianilinopyrimidine Containing Methanesulfonamide (TRE-069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

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All Science Journal Classification (ASJC) codes

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