Stratified mucin producing intraepithelial lesion

Yoon Jin Cha; Myoung Ju Koh; Young Tae Kim; Nam Hoon Cho

doi:10.1111/j.1755-9294.2012.01132.x

Stratified mucin producing intraepithelial lesion

Yoon Jin Cha, Myoung Ju Koh, Young Tae Kim, Nam Hoon Cho

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We report a case of stratified mucin producing intraepithelial lesion (SMILE), associated with adenocarcinoma and human papillomavirus (HPV) 18 infection. A 54-year-old lady presented with vaginal bleeding for 2 months. A punchy biopsy in private clinic showed papillary neoplasm composed of stratified columnar epithelium showing intracytoplasmic mucin vacuole. Microscopic examination for following cone biopsy demonstrated adenocarcinoma along with SMILE, and HPV 18 was detected by DNA chip examination. After several immunohistochemical stainings, SMILE showed predominant glandular differentiation.

Original language	English
Pages (from-to)	72-75
Number of pages	4
Journal	Basic and Applied Pathology
Volume	5
Issue number	3
DOIs	https://doi.org/10.1111/j.1755-9294.2012.01132.x
Publication status	Published - 2012 Sept

All Science Journal Classification (ASJC) codes

Pathology and Forensic Medicine

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10.1111/j.1755-9294.2012.01132.x

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abstract = "We report a case of stratified mucin producing intraepithelial lesion (SMILE), associated with adenocarcinoma and human papillomavirus (HPV) 18 infection. A 54-year-old lady presented with vaginal bleeding for 2 months. A punchy biopsy in private clinic showed papillary neoplasm composed of stratified columnar epithelium showing intracytoplasmic mucin vacuole. Microscopic examination for following cone biopsy demonstrated adenocarcinoma along with SMILE, and HPV 18 was detected by DNA chip examination. After several immunohistochemical stainings, SMILE showed predominant glandular differentiation.",

author = "Cha, {Yoon Jin} and Koh, {Myoung Ju} and Kim, {Young Tae} and Cho, {Nam Hoon}",

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AU - Koh, Myoung Ju

AU - Kim, Young Tae

AU - Cho, Nam Hoon

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N2 - We report a case of stratified mucin producing intraepithelial lesion (SMILE), associated with adenocarcinoma and human papillomavirus (HPV) 18 infection. A 54-year-old lady presented with vaginal bleeding for 2 months. A punchy biopsy in private clinic showed papillary neoplasm composed of stratified columnar epithelium showing intracytoplasmic mucin vacuole. Microscopic examination for following cone biopsy demonstrated adenocarcinoma along with SMILE, and HPV 18 was detected by DNA chip examination. After several immunohistochemical stainings, SMILE showed predominant glandular differentiation.

AB - We report a case of stratified mucin producing intraepithelial lesion (SMILE), associated with adenocarcinoma and human papillomavirus (HPV) 18 infection. A 54-year-old lady presented with vaginal bleeding for 2 months. A punchy biopsy in private clinic showed papillary neoplasm composed of stratified columnar epithelium showing intracytoplasmic mucin vacuole. Microscopic examination for following cone biopsy demonstrated adenocarcinoma along with SMILE, and HPV 18 was detected by DNA chip examination. After several immunohistochemical stainings, SMILE showed predominant glandular differentiation.

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Stratified mucin producing intraepithelial lesion

Abstract

All Science Journal Classification (ASJC) codes

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