Stabilization of α-helices by the self-assembly of macrocyclic peptides on the surface of gold nanoparticles for molecular recognition

Boram Kim; Sung Ju Choi; So Hee Han; Kang Yell Choi; Yong Beom Lim

doi:10.1039/c3cc44644a

Stabilization of α-helices by the self-assembly of macrocyclic peptides on the surface of gold nanoparticles for molecular recognition

Boram Kim, Sung Ju Choi, So Hee Han, Kang Yell Choi, Yong Beom Lim

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

A novel strategy to stabilize the α-helical secondary structures of peptides upon binding to gold nanoparticles is described. Using a model protein–protein interaction system, we showed that AuNPs decorated with stabilized p53 α-helix peptides can mediate specific molecular recognition with their target protein.

Original language	English
Pages (from-to)	7617-7619
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	69
DOIs	https://doi.org/10.1039/c3cc44644a
Publication status	Published - 2013 Aug 1

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c3cc44644a

Cite this

@article{be39949e9cb84ec497b4c7247da7f258,

title = "Stabilization of α-helices by the self-assembly of macrocyclic peptides on the surface of gold nanoparticles for molecular recognition",

abstract = "A novel strategy to stabilize the α-helical secondary structures of peptides upon binding to gold nanoparticles is described. Using a model protein–protein interaction system, we showed that AuNPs decorated with stabilized p53 α-helix peptides can mediate specific molecular recognition with their target protein.",

author = "Boram Kim and Choi, {Sung Ju} and Han, {So Hee} and Choi, {Kang Yell} and Lim, {Yong Beom}",

year = "2013",

month = aug,

day = "1",

doi = "10.1039/c3cc44644a",

language = "English",

volume = "49",

pages = "7617--7619",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "69",

}

TY - JOUR

T1 - Stabilization of α-helices by the self-assembly of macrocyclic peptides on the surface of gold nanoparticles for molecular recognition

AU - Kim, Boram

AU - Choi, Sung Ju

AU - Han, So Hee

AU - Choi, Kang Yell

AU - Lim, Yong Beom

PY - 2013/8/1

Y1 - 2013/8/1

N2 - A novel strategy to stabilize the α-helical secondary structures of peptides upon binding to gold nanoparticles is described. Using a model protein–protein interaction system, we showed that AuNPs decorated with stabilized p53 α-helix peptides can mediate specific molecular recognition with their target protein.

AB - A novel strategy to stabilize the α-helical secondary structures of peptides upon binding to gold nanoparticles is described. Using a model protein–protein interaction system, we showed that AuNPs decorated with stabilized p53 α-helix peptides can mediate specific molecular recognition with their target protein.

UR - http://www.scopus.com/inward/record.url?scp=84881175616&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881175616&partnerID=8YFLogxK

U2 - 10.1039/c3cc44644a

DO - 10.1039/c3cc44644a

M3 - Article

C2 - 23873019

AN - SCOPUS:84881175616

SN - 1359-7345

VL - 49

SP - 7617

EP - 7619

JO - Chemical Communications

JF - Chemical Communications

IS - 69

ER -

Stabilization of α-helices by the self-assembly of macrocyclic peptides on the surface of gold nanoparticles for molecular recognition

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this