Spinal cord involvement in Behçet's disease

Hyung Seok Lee; Do Young Kim; Ha Young Shin; Young Chul Choi; Seung Min Kim

doi:10.1177/1352458515613642

Spinal cord involvement in Behçet's disease

Hyung Seok Lee, Do Young Kim, Ha Young Shin, Young Chul Choi, Seung Min Kim

Department of Neurology

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Background: Spinal cord involvement in Behçet's disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet's disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet's disease. Results: The median age of onset for spinal cord involvement was 32 (23-45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet's disease.

Original language	English
Pages (from-to)	960-963
Number of pages	4
Journal	Multiple Sclerosis
Volume	22
Issue number	7
DOIs	https://doi.org/10.1177/1352458515613642
Publication status	Published - 2016 Jun 1

Bibliographical note

Publisher Copyright:
© SAGE Publications.

All Science Journal Classification (ASJC) codes

Neurology
Clinical Neurology

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Cite this

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title = "Spinal cord involvement in Beh{\c c}et's disease",

abstract = "Background: Spinal cord involvement in Beh{\c c}et's disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Beh{\c c}et's disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Beh{\c c}et's disease. Results: The median age of onset for spinal cord involvement was 32 (23-45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Beh{\c c}et's disease.",

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T1 - Spinal cord involvement in Behçet's disease

AU - Lee, Hyung Seok

AU - Kim, Do Young

AU - Shin, Ha Young

AU - Choi, Young Chul

AU - Kim, Seung Min

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Background: Spinal cord involvement in Behçet's disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet's disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet's disease. Results: The median age of onset for spinal cord involvement was 32 (23-45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet's disease.

AB - Background: Spinal cord involvement in Behçet's disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behçet's disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behçet's disease. Results: The median age of onset for spinal cord involvement was 32 (23-45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behçet's disease.

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Spinal cord involvement in Behçet's disease

Abstract

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