Spheroform: Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes

Mihyun Lee; Kisuk Yang; Yong Hwa Hwang; Youngro Byun; Dong Yun Lee; Seung Woo Cho; Haeshin Lee

doi:10.1002/adhm.201400429

Spheroform: Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes

Mihyun Lee, Kisuk Yang, Yong Hwa Hwang, Youngro Byun, Dong Yun Lee, Seung Woo Cho, Haeshin Lee

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

An approach is presented to create arrays of quasi-spherical microdroplets by surfaces called "spheroform" inspired by micro-/nanostructures found in the back of the Namib desert beetle. Spheroform is fabricated by microarray formation of catecholamine polymers on the superhydrophobic background. Spheroform is able to precisely control spheroid sizes of therapeutic islet cells and mesenchymal stem cells. The therapeutic spheroids exhibit improved biochemical activities.

Original language	English
Pages (from-to)	511-515
Number of pages	5
Journal	Advanced Healthcare Materials
Volume	4
Issue number	4
DOIs	https://doi.org/10.1002/adhm.201400429
Publication status	Published - 2015 Mar 1

Bibliographical note

Publisher Copyright:
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

All Science Journal Classification (ASJC) codes

Biomaterials
Biomedical Engineering
Pharmaceutical Science

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10.1002/adhm.201400429

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AU - Byun, Youngro

AU - Lee, Dong Yun

AU - Cho, Seung Woo

AU - Lee, Haeshin

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Spheroform: Therapeutic spheroid-forming nanotextured surfaces inspired by desert beetle physosterna cribripes

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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