Species distribution and macrolide susceptibility of mycobacterium fortuitum complex clinical isolates

Su Young Kim, Seong Mi Moon, Byung Woo Jhun, O. Jung Kwon, Hee Jae Huh, Nam Yong Lee, Seung Heon Lee, Sung Jae Shin, Shannon H. Kasperbauer, Gwen A. Huitt, Charles L. Daley, Won Jung Koh

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


The understanding of species distribution and inducible macrolide resistance in the Mycobacterium fortuitum complex (MFC) is limited. Of 90 mostly respiratory MFC clinical isolates, half were M. fortuitum, followed by M. peregrinum, M. porcinum, M. septicum, and M. conceptionense. Most M. fortuitum, M. porcinum, and M. septicum isolates were inducibly resistant to clarithromycin, whereas two-thirds of the M. peregrinum isolates were clarithromycin susceptible. Clarithromycin-resistant M. fortuitum isolates exhibited common mutations of erm(39), potentially involved in clarithromycin resistance.

Original languageEnglish
Article numbere02331-18
JournalAntimicrobial agents and chemotherapy
Issue number6
Publication statusPublished - 2019 Jun

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) funded by the South Korea government (MSIT) (NRF-2018R1A2A1A05018309).

Publisher Copyright:
© 2019 American Society for Microbiology. All Rights Reserved.

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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