Smoking, alcohol and gastric cancer risk in Korean men: The National Health Insurance Corporation Study

N. Y. Sung; K. S. Choi; E. C. Park; K. Park; S. Y. Lee; A. K. Lee; I. J. Choi; K. W. Jung; Y. J. Won; H. R. Shin

doi:10.1038/sj.bjc.6603893

Smoking, alcohol and gastric cancer risk in Korean men: The National Health Insurance Corporation Study

N. Y. Sung, K. S. Choi, E. C. Park, K. Park, S. Y. Lee, A. K. Lee, I. J. Choi, K. W. Jung, Y. J. Won, H. R. Shin

Department of Preventive Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

We investigated the risk of gastric cancer by subsite in relation to cigarette smoking and alcohol in a large population-based cohort of 669 570 Korean men in an insurance plan followed for an average 6.5 years, yielding 3452 new cases of gastric cancer, of which 127 were cardia and upper-third gastric cancer, 2409 were distal gastric cancer and 1007 were unclassified. A moderate association was found between smoking, cardia and upper-third (adjusted relative risk (aRR) 2.2; 95% confidence interval (CI) 1.4-3.5) and distal cancers (aRR=1.4; 95% CI=1.3-1.6). We also found a positive association between alcohol consumption and distal (aRR=1.3; 95% CI=1.2-1.5) and total (aRR=1.2; 95% CI=1.1-1.4) gastric cancer. Combined exposure to high levels of tobacco and alcohol increased the risk estimates further; cardia and upper-third gastric cancers were more strongly related to smoking status than distal gastric cancer.

Original language	English
Pages (from-to)	700-704
Number of pages	5
Journal	British journal of cancer
Volume	97
Issue number	5
DOIs	https://doi.org/10.1038/sj.bjc.6603893
Publication status	Published - 2007 Aug 28

Bibliographical note

Funding Information:
We thank the Korean Central Cancer Registry (KCCR) and the National Health Insurance Corporation for providing help. This work was supported by National Cancer Center grant 0710131-1.

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

UN SDGs

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10.1038/sj.bjc.6603893

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title = "Smoking, alcohol and gastric cancer risk in Korean men: The National Health Insurance Corporation Study",

abstract = "We investigated the risk of gastric cancer by subsite in relation to cigarette smoking and alcohol in a large population-based cohort of 669 570 Korean men in an insurance plan followed for an average 6.5 years, yielding 3452 new cases of gastric cancer, of which 127 were cardia and upper-third gastric cancer, 2409 were distal gastric cancer and 1007 were unclassified. A moderate association was found between smoking, cardia and upper-third (adjusted relative risk (aRR) 2.2; 95% confidence interval (CI) 1.4-3.5) and distal cancers (aRR=1.4; 95% CI=1.3-1.6). We also found a positive association between alcohol consumption and distal (aRR=1.3; 95% CI=1.2-1.5) and total (aRR=1.2; 95% CI=1.1-1.4) gastric cancer. Combined exposure to high levels of tobacco and alcohol increased the risk estimates further; cardia and upper-third gastric cancers were more strongly related to smoking status than distal gastric cancer.",

author = "Sung, {N. Y.} and Choi, {K. S.} and Park, {E. C.} and K. Park and Lee, {S. Y.} and Lee, {A. K.} and Choi, {I. J.} and Jung, {K. W.} and Won, {Y. J.} and Shin, {H. R.}",

note = "Funding Information: We thank the Korean Central Cancer Registry (KCCR) and the National Health Insurance Corporation for providing help. This work was supported by National Cancer Center grant 0710131-1.",

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doi = "10.1038/sj.bjc.6603893",

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T2 - The National Health Insurance Corporation Study

AU - Sung, N. Y.

AU - Choi, K. S.

AU - Park, E. C.

AU - Park, K.

AU - Lee, S. Y.

AU - Lee, A. K.

AU - Choi, I. J.

AU - Jung, K. W.

AU - Won, Y. J.

AU - Shin, H. R.

N1 - Funding Information: We thank the Korean Central Cancer Registry (KCCR) and the National Health Insurance Corporation for providing help. This work was supported by National Cancer Center grant 0710131-1.

PY - 2007/8/28

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N2 - We investigated the risk of gastric cancer by subsite in relation to cigarette smoking and alcohol in a large population-based cohort of 669 570 Korean men in an insurance plan followed for an average 6.5 years, yielding 3452 new cases of gastric cancer, of which 127 were cardia and upper-third gastric cancer, 2409 were distal gastric cancer and 1007 were unclassified. A moderate association was found between smoking, cardia and upper-third (adjusted relative risk (aRR) 2.2; 95% confidence interval (CI) 1.4-3.5) and distal cancers (aRR=1.4; 95% CI=1.3-1.6). We also found a positive association between alcohol consumption and distal (aRR=1.3; 95% CI=1.2-1.5) and total (aRR=1.2; 95% CI=1.1-1.4) gastric cancer. Combined exposure to high levels of tobacco and alcohol increased the risk estimates further; cardia and upper-third gastric cancers were more strongly related to smoking status than distal gastric cancer.

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Smoking, alcohol and gastric cancer risk in Korean men: The National Health Insurance Corporation Study

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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