TY - JOUR
T1 - Simple microdilution test for detection of metallo-β-lactamase production in pseudomonas aeruginosa
AU - Migliavacca, Roberta
AU - Docquier, Jean Denis
AU - Mugnaioli, Claudia
AU - Amicosante, Gianfranco
AU - Daturi, Rossana
AU - Lee, Kyungwon
AU - Rossolini, Gian Maria
AU - Pagani, Laura
PY - 2002/11/1
Y1 - 2002/11/1
N2 - A microdilution test measuring imipenem MICs in the presence or absence of a mixture of EDTA plus 1,10-phenanthroline was developed and tested on 190 Pseudomonas aeruginosa isolates, including 18 VIM-and 4 IMP-type metallo-β-lactamase (MBL) producers. The chelator mixture reduced by fourfold or more the imipenem MICs for MBL producers, while a lower effect or no effect was usually observed with MBL nonproducers.
AB - A microdilution test measuring imipenem MICs in the presence or absence of a mixture of EDTA plus 1,10-phenanthroline was developed and tested on 190 Pseudomonas aeruginosa isolates, including 18 VIM-and 4 IMP-type metallo-β-lactamase (MBL) producers. The chelator mixture reduced by fourfold or more the imipenem MICs for MBL producers, while a lower effect or no effect was usually observed with MBL nonproducers.
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U2 - 10.1128/JCM.40.11.4388-4390.2002
DO - 10.1128/JCM.40.11.4388-4390.2002
M3 - Article
C2 - 12409438
AN - SCOPUS:0036840059
SN - 0095-1137
VL - 40
SP - 4388
EP - 4390
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
IS - 11
ER -