Sexuality and the management of BPH with alfuzosin (SAMBA) trial

B. H. Chung, J. Y. Lee, C. I. Kim, C. S. Kim, C. Y. Oh, S. W. Lee, J. S. Lee, S. J. Yoo

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6 Citations (Scopus)


The sexuality and the management of benign prostatic hyperplasia (BPH) with alfuzosin (SAMBA) trial evaluated the effect of alfuzosin on sexual function in men treated for BPH using two sexual function scales: male sexual health questionnaire (MSHQ) and international index of erectile function (IIEF-15). A total of 148 patients with BPH were treated with alfuzosin for 24 weeks. The patients were followed at baseline, 4, 12 and 24 weeks after medication with alfuzosin. MSHQ was collected at every visit, whereas Qmax, IPSS and IIEF-15 were checked at baseline and end point. At the end point, Q max (+4.7 ml s-1, P<0.01) and IPSS (-5.3, P<0.01) had improved significantly. Alfuzosin also significantly improved the total MSHQ (19.2%, 79.1-94.3, P<0.01) and the MSHQ ejaculatory scores (26.0%, 22.3-28.1, P=<0.01) versus baseline. Alfuzosin for the treatment of patients with BPH is effective in improving sexual function, as well as lower urinary tract symptoms (LUTSs) and quality of life, and is well tolerated.

Original languageEnglish
Pages (from-to)68-73
Number of pages6
JournalInternational journal of impotence research
Issue number1
Publication statusPublished - 2009 Jan

Bibliographical note

Funding Information:
The SAMBA trial was sponsored by Sanofi-Aventis/ Handok pharmacy Inc., Korea.

All Science Journal Classification (ASJC) codes

  • Urology


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