Role of microsphere as drug carrier for osteogenic differentiation

Yuju Jun, Hyunyoung Oh, Rajshekhar Karpoormath, Amitabh Jha, Rajkumar Patel

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Drug delivery system in sustainable manner has a great potential in biomedical applications. Along with its biocompatibility, microspheres ability to encapsulate and promote sustained release of drugs or growth factor makes them an ideal carrier for the transport of bioactive molecules for tissue regeneration and controlled drug delivery applications. Additionally, the injectable form of small spherical microsphere facilitates the accurate drug delivery. These drug carrier microspheres have significant role in osteogenic differentiation. The invasive delivery of bioactive molecules promotes bone regeneration. The drug stimulates the osteogenic differentiation of stem cell and promotes the damaged tissue for self-repair. This review elaborates the role of polymeric microspheres and the composite microspheres as a drug carrier for osteogenic differentiation.

Original languageEnglish
Pages (from-to)318-327
Number of pages10
JournalInternational Journal of Polymeric Materials and Polymeric Biomaterials
Volume70
Issue number5
DOIs
Publication statusAccepted/In press - 2020

Bibliographical note

Publisher Copyright:
© 2020, © 2020 Taylor & Francis Group, LLC.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemical Engineering(all)
  • Polymers and Plastics

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