TY - GEN
T1 - RN-Cluster
T2 - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008
AU - Ahn, Jaegyoon
AU - Yoon, Youngmi
AU - Park, Sanghyun
PY - 2008
Y1 - 2008
N2 - A bicluster is a subset of genes that show similar behavior within a subset of conditions. Biclustering algorithm is a useful tool to uncover groups of genes involved in the same cellular process and groups of conditions which take place in this process. We are proposing a polynomial time algorithm to identify functionally highly correlated biclusters. Our algorithm identifies 1) the gene set that follows additive, multiplicative, and combined patterns simultaneously that allow high level of noise, 2) the multiple, possibly overlapped, and diverse gene sets, 3) biclusters with negatively correlated as well as positively correlated gene set simultaneously, and 4) gene sets whose functional association is strongly high. We validated the level of functional association of our method, and compared with current methods using GO.
AB - A bicluster is a subset of genes that show similar behavior within a subset of conditions. Biclustering algorithm is a useful tool to uncover groups of genes involved in the same cellular process and groups of conditions which take place in this process. We are proposing a polynomial time algorithm to identify functionally highly correlated biclusters. Our algorithm identifies 1) the gene set that follows additive, multiplicative, and combined patterns simultaneously that allow high level of noise, 2) the multiple, possibly overlapped, and diverse gene sets, 3) biclusters with negatively correlated as well as positively correlated gene set simultaneously, and 4) gene sets whose functional association is strongly high. We validated the level of functional association of our method, and compared with current methods using GO.
UR - http://www.scopus.com/inward/record.url?scp=52249088038&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=52249088038&partnerID=8YFLogxK
U2 - 10.1109/BIOTECHNO.2008.8
DO - 10.1109/BIOTECHNO.2008.8
M3 - Conference contribution
AN - SCOPUS:52249088038
SN - 9780769531915
T3 - Proceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008
SP - 131
EP - 136
BT - Proceedings - International Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, BIOTECHNO 2008
Y2 - 29 June 2008 through 5 July 2008
ER -