Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Minjeong Kim; Sung Kyun Ko; Hyemi Kim; Injae Shin; Jinsung Tae

doi:10.1039/c3cc44627a

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Minjeong Kim, Sung Kyun Ko, Hyemi Kim, Injae Shin, Jinsung Tae

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

A new rhodamine fluorescent probe for monitoring OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular OH in live cells.

Original language	English
Pages (from-to)	7959-7961
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	72
DOIs	https://doi.org/10.1039/c3cc44627a
Publication status	Published - 2013 Aug 13

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc44627a

Cite this

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abstract = "A new rhodamine fluorescent probe for monitoring OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular OH in live cells.",

author = "Minjeong Kim and Ko, {Sung Kyun} and Hyemi Kim and Injae Shin and Jinsung Tae",

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AU - Kim, Minjeong

AU - Ko, Sung Kyun

AU - Kim, Hyemi

AU - Shin, Injae

AU - Tae, Jinsung

PY - 2013/8/13

Y1 - 2013/8/13

N2 - A new rhodamine fluorescent probe for monitoring OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular OH in live cells.

AB - A new rhodamine fluorescent probe for monitoring OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular OH in live cells.

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EP - 7961

JO - Chemical Communications

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ER -

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Abstract

All Science Journal Classification (ASJC) codes

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