Report of aids-related lymphoma in South Korea

Jin Soo Kim, Seok Jin Kim, Jin Seok Kim, Eun Sun Kim, Ho Jin Shin, Joo Seop Chung, Yoo Hong Min, Moon Hee Lee, Young Jin Choi, Soo Mee Bang, Jung A. Kim, Goon Jae Cho, Hyun Sook Chi, Seong Soo Jang, Chan Jeoung Park, Cheolwon Suh, Chong Won Park, Chul Soo Kim

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Background: The prevalence of AIDS-related lymphoma (ARL) is increasing in South Korea. The aim of this study is to identify the clinical features of ARL in South Korea. Methods: From 1998 through 2006, we retrospectively analysed a total of 23 cases of ARL from seven institutions. Results: The patients consisted of 20 males and 3 females at a median age of 40 (range, 20-72) on diagnosis of AIDS. ARL developed at their median age of 41 (range, 24-72). The histological diagnosis was aggressive B cell lymphoma in the majority, but rare T cell and NK/T cell lymphoma were also included. Ten of 23 (43.5%) was receiving highly active anti-retroviral therapy (HAART) before the diagnosis of ARL. Fifteen of twenty-three patients were given combination chemotherapy with/without radiation, four were given radiation alone, and four did not receive any treatment against medical advice. Of 20 patients followed-up, nine were alive in remission, two alive in disease, one died of treatment related complication, four died of progressive lymphoma, four died of AIDS related causes. The response to treatment included CR in eight (44.4%), PR in four (22.2%) and PD in three (16.7%). The response to HARRT was evaluable in 13 patients based on CD4+ cell count and HIV viral load, among which nine (69.2%) responded. Estimated median survival time was 43.9 months. Conclusions: Although the population of patients is small, this is the first clinical data analyses of Korean ARL patients. As a substantial portion of the patients remains alive disease free, the impact of HAART on the clinical course of ARL needs further follow-up and evaluation.

Original languageEnglish
Pages (from-to)134-139
Number of pages6
JournalJapanese Journal of Clinical Oncology
Issue number2
Publication statusPublished - 2008 Feb

Bibliographical note

Funding Information:
This study was supported by Inha University Research Grant.

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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