TY - JOUR
T1 - Repetitive involuntary leg movements in patients with brainstem lesions involving the pontine tegmentum
T2 - Evidence for a pontine inhibitory region in humans
AU - Lee, Phil Hyu
AU - Lee, Jin Soo
AU - Yong, Seok Woo
AU - Huh, Kyoon
PY - 2005/3
Y1 - 2005/3
N2 - Repetitive involuntary limbs movements have been mostly reported in patients with extensive brainstem pathologies, but the region responsible is unknown. We describe two patients with progressive basilar artery infarcts who showed automatic stepping and one patient with an osmotic demyelination disorder who showed periodic involuntary leg movements. By subtracting diffusion-weighted images before and after the development of repetitive involuntary leg movements, the brainstem lesion responsible for the involuntary movements was distinctively located in the vicinity of the pontine tegmentum, which is known as the pontine inhibitory region in animal studies.
AB - Repetitive involuntary limbs movements have been mostly reported in patients with extensive brainstem pathologies, but the region responsible is unknown. We describe two patients with progressive basilar artery infarcts who showed automatic stepping and one patient with an osmotic demyelination disorder who showed periodic involuntary leg movements. By subtracting diffusion-weighted images before and after the development of repetitive involuntary leg movements, the brainstem lesion responsible for the involuntary movements was distinctively located in the vicinity of the pontine tegmentum, which is known as the pontine inhibitory region in animal studies.
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U2 - 10.1016/j.parkreldis.2004.09.005
DO - 10.1016/j.parkreldis.2004.09.005
M3 - Article
C2 - 15734669
AN - SCOPUS:14044257334
SN - 1353-8020
VL - 11
SP - 105
EP - 110
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
IS - 2
ER -