Release of bisphenol a from pit and fissure sealants according to different pH conditions

Eun Deok Jo, Sang Bae Lee, Chung Min Kang, Kwang Mahn Kim, Jae Sung Kwon

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Changes in intraoral pH can cause changes in the chemical decomposition and surface properties of treated resin-based pits and fissure sealants (sealant). The purpose of this study is to evaluate the release of bisphenol A (BPA) from sealants under three different pH conditions over time. The test specimen was applied with 6 sealants 5 mg each on a glass plate (10 × 10 mm) and photopolymerized. The samples were immersed for 10 min, 1 h, and 24 h in solutions of pH 3.0, 6.5, and 10.0 at 37C. BPA release was measured using a gas chromatography-mass spectrometer. A statistical analysis was performed by two-way ANOVA and one-way ANOVA to verify the effect of pH conditions and time on BPA release. The BPA concentration in the pH 3.0 group was higher at all points than with pH 6.5 and pH 10.0 (p < 0.05), and gradually increased over time (p < 0.05). As a result, it was confirmed that low pH negatively influences BPA release. Therefore, frequent exposure to low pH due to the consumption of various beverages after sealant treatment can negatively affect the sealant’s chemical stability in the oral cavity.

Original languageEnglish
Article number37
Issue number1
Publication statusPublished - 2022 Jan 1

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Polymers and Plastics


Dive into the research topics of 'Release of bisphenol a from pit and fissure sealants according to different pH conditions'. Together they form a unique fingerprint.

Cite this