Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients

W. I. Yang; S. H. Lee; Y. G. Ko; S. M. Kang; D. Choi; J. W. Ha; M. K. Hong; N. Chung; W. H. Shim; S. Y. Cho; Y. Jang

doi:10.1038/jhh.2010.10

Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients

W. I. Yang, S. H. Lee, Y. G. Ko, S. M. Kang, D. Choi, J. W. Ha, M. K. Hong, N. Chung, W. H. Shim, S. Y. Cho, Y. Jang

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Low paraoxonase-1 (PON1) activity has been regarded as one of risk factors for cardiovascular disease. We showed that low PON1 activity was independently associated with carotid intima-media thickness (IMT) and heart to femoral pulse wave velocity (hfPWV) in hypertensive patients. Our results indicate that PON1 activity may reflect early structural and functional changes of arteries in this population.

Original language	English
Pages (from-to)	492-494
Number of pages	3
Journal	Journal of Human Hypertension
Volume	24
Issue number	7
DOIs	https://doi.org/10.1038/jhh.2010.10
Publication status	Published - 2010 Jul

Bibliographical note

Funding Information:
This study was supported by a grant (A000385) from the Ministry of Health and Welfare, Republic of Korea, a grant from the Seoul R&BD Program, Republic of Korea (10526) and a grant from the Korean Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A085136).

All Science Journal Classification (ASJC) codes

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/jhh.2010.10

Cite this

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title = "Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients",

abstract = "Low paraoxonase-1 (PON1) activity has been regarded as one of risk factors for cardiovascular disease. We showed that low PON1 activity was independently associated with carotid intima-media thickness (IMT) and heart to femoral pulse wave velocity (hfPWV) in hypertensive patients. Our results indicate that PON1 activity may reflect early structural and functional changes of arteries in this population.",

author = "Yang, {W. I.} and Lee, {S. H.} and Ko, {Y. G.} and Kang, {S. M.} and D. Choi and Ha, {J. W.} and Hong, {M. K.} and N. Chung and Shim, {W. H.} and Cho, {S. Y.} and Y. Jang",

note = "Funding Information: This study was supported by a grant (A000385) from the Ministry of Health and Welfare, Republic of Korea, a grant from the Seoul R&BD Program, Republic of Korea (10526) and a grant from the Korean Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A085136).",

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doi = "10.1038/jhh.2010.10",

language = "English",

volume = "24",

pages = "492--494",

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AU - Yang, W. I.

AU - Lee, S. H.

AU - Ko, Y. G.

AU - Kang, S. M.

AU - Choi, D.

AU - Ha, J. W.

AU - Hong, M. K.

AU - Chung, N.

AU - Shim, W. H.

AU - Cho, S. Y.

AU - Jang, Y.

N1 - Funding Information: This study was supported by a grant (A000385) from the Ministry of Health and Welfare, Republic of Korea, a grant from the Seoul R&BD Program, Republic of Korea (10526) and a grant from the Korean Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A085136).

PY - 2010/7

Y1 - 2010/7

N2 - Low paraoxonase-1 (PON1) activity has been regarded as one of risk factors for cardiovascular disease. We showed that low PON1 activity was independently associated with carotid intima-media thickness (IMT) and heart to femoral pulse wave velocity (hfPWV) in hypertensive patients. Our results indicate that PON1 activity may reflect early structural and functional changes of arteries in this population.

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Relationship between paraoxonase-1 activity, carotid intima-media thickness and arterial stiffness in hypertensive patients

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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