Regiospecific Synthesis of 5- and 6-Acylated Naphtho[1,2- b ]benzofurans via Intramolecular Alkyne Carbonyl Metathesis

Maloy Nayak; Dileep Kumar Singh; Ikyon Kim

doi:10.1055/s-0036-1588120

Regiospecific Synthesis of 5- and 6-Acylated Naphtho[1,2- b ]benzofurans via Intramolecular Alkyne Carbonyl Metathesis

Maloy Nayak, Dileep Kumar Singh, Ikyon Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Straightforward access to various 5- and 6-acylated naphtho[1,2-b]benzofurans was achieved by successive Sonogashira coupling and intramolecular alkyne carbonyl metathesis to assemble the central aromatic C ring of naphtho[1,2-b]benzofurans regiospecifically substituted with an acyl group at the C5 or C6 position.

Original language	English
Article number	ss-2016-f0747-op
Pages (from-to)	2063-2073
Number of pages	11
Journal	Synthesis (Germany)
Volume	49
Issue number	9
DOIs	https://doi.org/10.1055/s-0036-1588120
Publication status	Published - 2017 May 3

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (2014R1A2A1A11050491).

Publisher Copyright:
© Georg Thieme Verlag Stuttgart · New York-Synthesis 2017.

All Science Journal Classification (ASJC) codes

Catalysis
Organic Chemistry

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abstract = "Straightforward access to various 5- and 6-acylated naphtho[1,2-b]benzofurans was achieved by successive Sonogashira coupling and intramolecular alkyne carbonyl metathesis to assemble the central aromatic C ring of naphtho[1,2-b]benzofurans regiospecifically substituted with an acyl group at the C5 or C6 position.",

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AU - Singh, Dileep Kumar

AU - Kim, Ikyon

N1 - Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (2014R1A2A1A11050491). Publisher Copyright: © Georg Thieme Verlag Stuttgart · New York-Synthesis 2017.

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AB - Straightforward access to various 5- and 6-acylated naphtho[1,2-b]benzofurans was achieved by successive Sonogashira coupling and intramolecular alkyne carbonyl metathesis to assemble the central aromatic C ring of naphtho[1,2-b]benzofurans regiospecifically substituted with an acyl group at the C5 or C6 position.

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Regiospecific Synthesis of 5- and 6-Acylated Naphtho[1,2- b ]benzofurans via Intramolecular Alkyne Carbonyl Metathesis

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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