Real-time measurement of human salivary cortisol for the assessment of psychological stress using a smartphone

Seoyoen Choi; Soocheol Kim; Jung Sik Yang; Jung Hyun Lee; Chulmin Joo; Hyo Il Jung

doi:10.1016/j.sbsr.2014.08.001

Real-time measurement of human salivary cortisol for the assessment of psychological stress using a smartphone

Seoyoen Choi, Soocheol Kim, Jung Sik Yang, Jung Hyun Lee, Chulmin Joo, Hyo Il Jung

Department of Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

We present a simple smartphone-based measurement system consisting of a smartphone, a holder, and a lateral flow immune strip. The smartphone camera and light source were used to read the colorimetric signal from the lateral flow assay. A smartphone application was written and installed onto the smartphone. Various concentrations of cortisol were successfully measured using the images captured by the smartphone. Measurement of human salivary cortisol was then demonstrated using the lateral flow assay and the quantitative analysis was validated with the smartphone. The system was further evaluated using human saliva, demonstrating an accurate and reproducible platform for rapid and point-of-care quantification of cortisol using a smartphone-based measurement system.

Original language	English
Pages (from-to)	8-11
Number of pages	4
Journal	Sensing and Bio-Sensing Research
Volume	2
DOIs	https://doi.org/10.1016/j.sbsr.2014.08.001
Publication status	Published - 2014 Dec 1

Bibliographical note

Funding Information:
This work was supported by the Center for BioNano Health-Guard funded by the Ministry of Science, ICT & Future Planning (MSIP) of Korea as a Global Frontier Project (H-GUARD_2013M3A6B2078959) and by the R&D Program of the Ministry of Trade, Industry and Energy of Korea (Program of Advanced Technology Development for Future Industry, 10044399).

Publisher Copyright:
© 2014 The Authors.

All Science Journal Classification (ASJC) codes

Biotechnology
Electronic, Optical and Magnetic Materials
Signal Processing
Electrical and Electronic Engineering

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10.1016/j.sbsr.2014.08.001

Cite this

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title = "Real-time measurement of human salivary cortisol for the assessment of psychological stress using a smartphone",

abstract = "We present a simple smartphone-based measurement system consisting of a smartphone, a holder, and a lateral flow immune strip. The smartphone camera and light source were used to read the colorimetric signal from the lateral flow assay. A smartphone application was written and installed onto the smartphone. Various concentrations of cortisol were successfully measured using the images captured by the smartphone. Measurement of human salivary cortisol was then demonstrated using the lateral flow assay and the quantitative analysis was validated with the smartphone. The system was further evaluated using human saliva, demonstrating an accurate and reproducible platform for rapid and point-of-care quantification of cortisol using a smartphone-based measurement system.",

author = "Seoyoen Choi and Soocheol Kim and Yang, {Jung Sik} and Lee, {Jung Hyun} and Chulmin Joo and Jung, {Hyo Il}",

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AU - Lee, Jung Hyun

AU - Joo, Chulmin

AU - Jung, Hyo Il

N1 - Funding Information: This work was supported by the Center for BioNano Health-Guard funded by the Ministry of Science, ICT & Future Planning (MSIP) of Korea as a Global Frontier Project (H-GUARD_2013M3A6B2078959) and by the R&D Program of the Ministry of Trade, Industry and Energy of Korea (Program of Advanced Technology Development for Future Industry, 10044399). Publisher Copyright: © 2014 The Authors.

PY - 2014/12/1

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N2 - We present a simple smartphone-based measurement system consisting of a smartphone, a holder, and a lateral flow immune strip. The smartphone camera and light source were used to read the colorimetric signal from the lateral flow assay. A smartphone application was written and installed onto the smartphone. Various concentrations of cortisol were successfully measured using the images captured by the smartphone. Measurement of human salivary cortisol was then demonstrated using the lateral flow assay and the quantitative analysis was validated with the smartphone. The system was further evaluated using human saliva, demonstrating an accurate and reproducible platform for rapid and point-of-care quantification of cortisol using a smartphone-based measurement system.

AB - We present a simple smartphone-based measurement system consisting of a smartphone, a holder, and a lateral flow immune strip. The smartphone camera and light source were used to read the colorimetric signal from the lateral flow assay. A smartphone application was written and installed onto the smartphone. Various concentrations of cortisol were successfully measured using the images captured by the smartphone. Measurement of human salivary cortisol was then demonstrated using the lateral flow assay and the quantitative analysis was validated with the smartphone. The system was further evaluated using human saliva, demonstrating an accurate and reproducible platform for rapid and point-of-care quantification of cortisol using a smartphone-based measurement system.

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Real-time measurement of human salivary cortisol for the assessment of psychological stress using a smartphone

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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