Ratiometric fluorescent determination of Zn(II): A new class of tripodal receptor using mixed imine and amide linkages

Doo Youn Lee; Narinder Singh; Min Joung Kim; Doo Ok Jang

doi:10.1016/j.tet.2010.08.024

Ratiometric fluorescent determination of Zn(II): A new class of tripodal receptor using mixed imine and amide linkages

Doo Youn Lee, Narinder Singh, Min Joung Kim, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

We synthesized a novel receptor with a unique combination of sp² nitrogen (-CH=N-) and carbonyl groups from amide linkages. These two moieties are judiciously incorporated into the receptor design such that these sites simultaneous binding a metal ion may generate a stable five-member ring. The receptor has been used to selectively detect Zn²⁺ through changes in the fluorescence spectra. Upon Zn²⁺ binding with the receptor, the fluorescence band shifted to enhance fluorescence intensity, allowing ratiometric determination of Zn²⁺ concentration.

Original language	English
Pages (from-to)	7965-7969
Number of pages	5
Journal	Tetrahedron
Volume	66
Issue number	40
DOIs	https://doi.org/10.1016/j.tet.2010.08.024
Publication status	Published - 2010 Oct 2

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (No. R11-2003-019-00000-0 ).

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tet.2010.08.024

Cite this

@article{dcf99e0fcccd4d17a1946abb36afea27,

title = "Ratiometric fluorescent determination of Zn(II): A new class of tripodal receptor using mixed imine and amide linkages",

abstract = "We synthesized a novel receptor with a unique combination of sp2 nitrogen (-CH=N-) and carbonyl groups from amide linkages. These two moieties are judiciously incorporated into the receptor design such that these sites simultaneous binding a metal ion may generate a stable five-member ring. The receptor has been used to selectively detect Zn2+ through changes in the fluorescence spectra. Upon Zn2+ binding with the receptor, the fluorescence band shifted to enhance fluorescence intensity, allowing ratiometric determination of Zn2+ concentration.",

author = "Lee, {Doo Youn} and Narinder Singh and Kim, {Min Joung} and Jang, {Doo Ok}",

note = "Funding Information: This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (No. R11-2003-019-00000-0 ). ",

year = "2010",

month = oct,

day = "2",

doi = "10.1016/j.tet.2010.08.024",

language = "English",

volume = "66",

pages = "7965--7969",

journal = "Tetrahedron",

issn = "0040-4020",

publisher = "Elsevier Limited",

number = "40",

}

TY - JOUR

T1 - Ratiometric fluorescent determination of Zn(II)

T2 - A new class of tripodal receptor using mixed imine and amide linkages

AU - Lee, Doo Youn

AU - Singh, Narinder

AU - Kim, Min Joung

AU - Jang, Doo Ok

N1 - Funding Information: This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (No. R11-2003-019-00000-0 ).

PY - 2010/10/2

Y1 - 2010/10/2

N2 - We synthesized a novel receptor with a unique combination of sp2 nitrogen (-CH=N-) and carbonyl groups from amide linkages. These two moieties are judiciously incorporated into the receptor design such that these sites simultaneous binding a metal ion may generate a stable five-member ring. The receptor has been used to selectively detect Zn2+ through changes in the fluorescence spectra. Upon Zn2+ binding with the receptor, the fluorescence band shifted to enhance fluorescence intensity, allowing ratiometric determination of Zn2+ concentration.

AB - We synthesized a novel receptor with a unique combination of sp2 nitrogen (-CH=N-) and carbonyl groups from amide linkages. These two moieties are judiciously incorporated into the receptor design such that these sites simultaneous binding a metal ion may generate a stable five-member ring. The receptor has been used to selectively detect Zn2+ through changes in the fluorescence spectra. Upon Zn2+ binding with the receptor, the fluorescence band shifted to enhance fluorescence intensity, allowing ratiometric determination of Zn2+ concentration.

UR - http://www.scopus.com/inward/record.url?scp=77956394737&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77956394737&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2010.08.024

DO - 10.1016/j.tet.2010.08.024

M3 - Article

AN - SCOPUS:77956394737

SN - 0040-4020

VL - 66

SP - 7965

EP - 7969

JO - Tetrahedron

JF - Tetrahedron

IS - 40

ER -

Ratiometric fluorescent determination of Zn(II): A new class of tripodal receptor using mixed imine and amide linkages

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this