Ratiometric and simultaneous estimation of Fe3+ and Cu 2+ ions: 1,3,5-substituted triethylbenzene derivatives coupled with benzimidazole

Doo Youn Lee; Narinder Singh; Doo Ok Jang

doi:10.1016/j.tetlet.2011.05.078

Ratiometric and simultaneous estimation of Fe³⁺ and Cu ²⁺ ions: 1,3,5-substituted triethylbenzene derivatives coupled with benzimidazole

Doo Youn Lee, Narinder Singh, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

We synthesized a novel 1,3,5-substituted triethylbenzene derivative with a benzimidazole moiety as a binding and signalling subunit. The triethylbenzene platform was judiciously incorporated into the receptor design such that all the fluorophores are in close proximity to each other in order to facilitate stacking. The advantage of this approach lies in the fact that the receptor will offer a dual channel emission for the multiple ratiometric determination of metal ions. The sensor was tested in a CH₃CN/H₂O (7:3, v/v, pH 7.1) HEPES buffered solution and successfully developed for the ratiometric and simultaneous estimation of Fe³⁺ and Cu²⁺ ions in aqueous samples.

Original language	English
Pages (from-to)	3886-3890
Number of pages	5
Journal	Tetrahedron Letters
Volume	52
Issue number	30
DOIs	https://doi.org/10.1016/j.tetlet.2011.05.078
Publication status	Published - 2011 Jul 27

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (NO. R11-2003-019-00000-0 ).

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2011.05.078

Cite this

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title = "Ratiometric and simultaneous estimation of Fe3+ and Cu 2+ ions: 1,3,5-substituted triethylbenzene derivatives coupled with benzimidazole",

abstract = "We synthesized a novel 1,3,5-substituted triethylbenzene derivative with a benzimidazole moiety as a binding and signalling subunit. The triethylbenzene platform was judiciously incorporated into the receptor design such that all the fluorophores are in close proximity to each other in order to facilitate stacking. The advantage of this approach lies in the fact that the receptor will offer a dual channel emission for the multiple ratiometric determination of metal ions. The sensor was tested in a CH3CN/H2O (7:3, v/v, pH 7.1) HEPES buffered solution and successfully developed for the ratiometric and simultaneous estimation of Fe3+ and Cu2+ ions in aqueous samples.",

author = "Lee, {Doo Youn} and Narinder Singh and Jang, {Doo Ok}",

note = "Funding Information: This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (NO. R11-2003-019-00000-0 ). ",

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T2 - 1,3,5-substituted triethylbenzene derivatives coupled with benzimidazole

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AU - Singh, Narinder

AU - Jang, Doo Ok

N1 - Funding Information: This work was supported by the National Research Foundation (NRF) grant funded by the Korea government (MEST) through the Center for Bioactive Molecular Hybrids (NO. R11-2003-019-00000-0 ).

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