Randomized comparison of acute stent malapposition between platinum–chromium versus cobalt–chromium everolimus-eluting stents

Byeong Keuk Kim, Dong Ho Shin, Jung Sun Kim, Young Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong Ki Hong

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12 Citations (Scopus)


No randomized data exist regarding optical coherence tomography (OCT) evaluation immediately post-procedure and at the 3-month follow-up for platinum–chromium everolimus-eluting stents (PtCr-EES) versus cobalt-chromium everolimus-eluting stents (CoCr-EES). A total of 100 patients were randomly assigned to undergo PtCr-EES (n = 51) or CoCr-EES (n = 49) implantation. OCT was serially evaluated after stent deployment with nominal pressure and immediately post-procedure, and 3-month follow-up. The primary endpoint was the percentage of malapposed strut after nominal pressure and immediately post-procedure. Compared to the CoCr-EES, the PtCr-EES showed a lower tendency of percent malapposed strut at nominal pressure [median value (interquartile range); 4.1 % (0.5–11.7) vs. 7.6 % (2.9–13.7), p = 0.082] and immediately post–procedure [1.2 % (0–3.4) vs. 2.5 % (0.7–5.3), p = 0.051]. The percentage of cross sections with any malapposed struts was significantly lower with PtCr-EES at nominal pressure [15.0 % (5.6–39.0) vs. 23.8 % (18.2–44.4), p = 0.036] and immediately post-procedure [6.5 % (0–15.3) vs. 10.5 % (7.1–20.0), p = 0.026]. At the 3-month follow-up, both PtCr-EES and CoCr-EES showed comparable percentages of malapposed struts (0 vs. 0 %, respectively, p = 0.332) and uncovered struts (5.3 vs. 4.7 %, respectively, p = 0.829). We found a significant correlation between the immediate post-procedural percentage of malapposed struts versus the percentage of uncovered struts (r = 0.430, p < 0.001) at the 3-month follow-up. Compared to the CoCr-EES, the PtCr-EES shows a lower tendency toward a lower percentage of malapposed struts but no significant difference in strut coverage at the 3-month follow-up. The percentage of malapposed struts immediately post-procedure was correlated with strut coverage at the 3-month follow-up.

Original languageEnglish
Pages (from-to)269-277
Number of pages9
JournalInternational Journal of Cardiovascular Imaging
Issue number2
Publication statusPublished - 2015 Feb 27

Bibliographical note

Funding Information:
This study was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (Nos. A085012, A102064), a grant from the Korea Health 21 R&D Project, Ministry of Health and Welfare, Republic of Korea (No. A085136), and the Cardiovascular Research Center, Seoul, Korea.

Publisher Copyright:
© 2014, Springer Science+Business Media Dordrecht.

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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