Radical deoxygenation of alcohols and intermolecular carbon-carbon bond formation with surfactant-type radical chain carriers in water

Dae Hyan Cho; Doo Ok Jang

doi:10.1016/j.tetlet.2005.01.107

Radical deoxygenation of alcohols and intermolecular carbon-carbon bond formation with surfactant-type radical chain carriers in water

Dae Hyan Cho, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

An efficient and mild method is developed for radical deoxygenation of alcohols and formation of carbon-carbon bonds in water without adding additives such as surfactants. The reaction was applied to synthesis of 2′,3′-didehydro-2′,3′-dideoxynucleosides that are potent anti-HIV agents. The reaction afforded environmentally benign reaction conditions.

Original language	English
Pages (from-to)	1799-1802
Number of pages	4
Journal	Tetrahedron Letters
Volume	46
Issue number	11
DOIs	https://doi.org/10.1016/j.tetlet.2005.01.107
Publication status	Published - 2005 Mar 14

Bibliographical note

Funding Information:
This work was supported by Korea Research Foundation Grant (KRF-2003-002-C00155).

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tetlet.2005.01.107

Cite this

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abstract = "An efficient and mild method is developed for radical deoxygenation of alcohols and formation of carbon-carbon bonds in water without adding additives such as surfactants. The reaction was applied to synthesis of 2′,3′-didehydro-2′,3′-dideoxynucleosides that are potent anti-HIV agents. The reaction afforded environmentally benign reaction conditions.",

author = "Cho, {Dae Hyan} and Jang, {Doo Ok}",

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AU - Jang, Doo Ok

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PY - 2005/3/14

Y1 - 2005/3/14

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AB - An efficient and mild method is developed for radical deoxygenation of alcohols and formation of carbon-carbon bonds in water without adding additives such as surfactants. The reaction was applied to synthesis of 2′,3′-didehydro-2′,3′-dideoxynucleosides that are potent anti-HIV agents. The reaction afforded environmentally benign reaction conditions.

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Radical deoxygenation of alcohols and intermolecular carbon-carbon bond formation with surfactant-type radical chain carriers in water

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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