Protein-losing enteropathy as a complication of the ketogenic diet

Won Kee Ahn, Soyoung Park, Heung Dong Kim

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The ketogenic diet is an effective treatment for the patients with intractable epilepsy, however, the diet therapy can sometimes be discontinued by complications. Protein-losing enteropathy is a rarely reported serious complication of the ketogenic diet. We present a 16-month-old Down syndrome baby with protein-losing enteropathy during the ketogenic diet as a treatment for West syndrome. He suffered from diarrhea, general edema and hypoalbuminemia which were not controlled by conservative care for over 1 month. Esophagogastroduodenoscopy and stool alpha-1 antitrypsin indicated protein-losing enteropathy. Related symptoms were relieved after cessation of the ketogenic diet. Unexplained hypoalbuminemia combined with edema and diarrhea during ketogenic suggests the possibility of protein-losing enteropathy, and proper evaluation is recommended in order to expeditiously detect it and to act accordingly.

Original languageEnglish
Pages (from-to)891-893
Number of pages3
JournalYonsei medical journal
Issue number4
Publication statusPublished - 2017 Jul

Bibliographical note

Publisher Copyright:
© Yonsei University College of Medicine 2017.

All Science Journal Classification (ASJC) codes

  • General Medicine


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