Promoted cell and material interaction on atmospheric pressure plasma treated titanium

Inho Han, Barbora Vagaska, Hyok Jin Seo, Jae Kyeong Kang, Byeong Ju Kwon, Mi Hee Lee, Jong Chul Park

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Surface carbon contamination is a natural phenomenon. However, it interferes with cell-biomaterial interaction. In order to eliminate the interference, atmospheric pressure plasma treatment was employed. Dielectric barrier discharge treatment of titanium surface for less than 10 min turned titanium super-hydrophilic. Adsorption of fibronectin which is the major cell adhesive protein increased after plasma treatment. Cell attachment parameters of osteoblast cells such as population, cell area, perimeter, Feret's diameter and cytoskeleton development were also enhanced. Cell proliferation increased on the plasma treated titanium. In conclusion, dielectric barrier discharge type atmospheric pressure plasma system is effective to modify titanium surface and the modified titanium promotes cell and material interactions.

Original languageEnglish
Pages (from-to)4718-4723
Number of pages6
JournalApplied Surface Science
Issue number10
Publication statusPublished - 2012 Mar 1

Bibliographical note

Funding Information:
This work was supported by National Research Foundation (NRF) of Korea Grant funded by the Korean Government (MEST) (grant number 2010-0002089 ) and was supported by a grant of the Korea Healthcare technology R&D Project, Ministry for Health & Welfare, Republic of Korea (grant number A100834 ). This article is dedicated to I. Han's lovely wife (Jeehae Choi) and pretty children (Jisu Han and Sangyoon Han).

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces


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