Primary malignant mucosal melanoma of the maxillofacial area

Hyounmin Kim, Sanghoon Lee, In Ho Cha, Hyung Jun Kim, Woong Nam

Research output: Contribution to journalArticlepeer-review


Objectives: We aimed to collect and report data from all patients who have been diagnosed with mucosal malignant melanoma to obtain the epidemiology and principles of current treatments. Materials and Methods: Between January 2008 and December 2018, 20 patients underwent surgery or follow-up observations at Yonsei University Dental Hospital. The patients' clinical information was reviewed retrospectively. Results: Seventeen of 20 patients had undergone definitive surgery, while only 6 patients received adjuvant radiotherapy or systemic therapy. Eight of 20 patients, including those that had recurrent lesions, were provided immunotherapy. The 3-year survival for all stages was 50%, with a local recurrence rate of 75% and a metastasis rate of 65%. Conclusion: The overall survival of patients receiving surgical treatment was longer than that of patients who did not undergo surgical resection. Eight of 20 patients received immunotherapy as the first-line regimen at our clinic, and those patients exhibited longer overall survival compared to patients in reported keynote studies.

Original languageEnglish
Pages (from-to)76-81
Number of pages6
JournalJournal of the Korean Association of Oral and Maxillofacial Surgeons
Issue number2
Publication statusPublished - 2021 Apr 30

Bibliographical note

Publisher Copyright:
Copyright © 2021 The Korean Association of Oral and Maxillofacial Surgeons.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery


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