Presence of metabolic syndrome components is associated with tooth loss in middle-aged adults

Min Jeong Cho, Youn Hee Choi, Hyeon Chang Kim, Jee Seon Shim, Atsuo Amano, Ji Young Kim, Keun Bae Song

Research output: Contribution to journalArticlepeer-review


Purpose: In general, the prevalence of metabolic syndrome (MS) and tooth loss increases with age. We investigated the relationship between the presence of MS, its elements, and tooth loss in middle-aged Korean adults. Materials and Methods: This study included Korean adults between 30 and 64 years of age who resided in the capital area of Seoul. From January to June 2014, individuals interested in participating in the oral health survey among those who visited the university hospital’s cardiovascular center and provided informed consent were selected. Among 748 subjects who responded to the oral health questionnaires, 30 were excluded due to unclear responses; therefore, a total of 718 were included in the final analysis. Results: The crude odds ratio (OR) of ≥one MS component affecting tooth loss was 1.45 [95% confidence interval (CI), 1.06-2.00]. After adjusting for sex, age, education, income level, occupation, smoking status, kidney disease, chronic obstructive pulmonary disease, and rheumatic disease, the adjusted OR was 1.47 (95% CI, 1.06-2.05), which was statistically significant (p<0.05). The OR for tooth loss was higher in the presence of ≥one component of MS (50-64 years of age) in females. Conclusion: This study suggests that female aged 50-64 years may have higher likelihood of tooth loss upon the presence of at least one MS component. Prevention against MS among female of older age could contribute to maintenance of remaining teeth. Further well-designed studies are needed.

Original languageEnglish
Pages (from-to)554-560
Number of pages7
JournalYonsei medical journal
Issue number6
Publication statusPublished - 2019 Jun

Bibliographical note

Funding Information:
This work was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI13C0715), the Ministry of Education of the Republic of Korea, and the National Research Foundation of Korea (NRF-2017S1A 3A2067165).

Publisher Copyright:
© Yonsei University College of Medicine 2019.

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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