Pre-natal and post-natal exposure to pet ownership and lung function in children: The Seven Northeastern Cities Study

L. W. Hu; Z. Qian; S. C. Dharmage; E. Liu; S. W. Howard; M. G. Vaughn; J. Perret; C. C. Lodge; X. W. Zeng; B. Y. Yang; S. L. Xu; C. Zhang; G. H. Dong

doi:10.1111/ina.12401

Pre-natal and post-natal exposure to pet ownership and lung function in children: The Seven Northeastern Cities Study

L. W. Hu, Z. Qian, S. C. Dharmage, E. Liu, S. W. Howard, M. G. Vaughn, J. Perret, C. C. Lodge, X. W. Zeng, B. Y. Yang, S. L. Xu, C. Zhang, G. H. Dong

Graduate School of Social Welfare

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

To evaluate the association between pre-natal and post-natal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV₁), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), and peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations were collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1.28; 95% confidence interval [CI]: 1.01, 1.63). For current pet exposure, the increased odds of lung function impairment ranged from 35% (aOR=1.35; 95%CI: 1.12, 1.62) for FVC<85% predicted to 57% (aOR=1.57; 95%CI: 1.29, 1.93) for FEV₁<85% predicted. The in utero exposure was not related to lung function impairment. Compared with other pets, higher odds were observed among children with dogs. When stratified by gender, girls with current pet exposure were more likely to have lung function impairment than boys. It implies self-reported exposures to pets were negatively associated with lung function among the children under study.

Original language	English
Pages (from-to)	1177-1189
Number of pages	13
Journal	Indoor Air
Volume	27
Issue number	6
DOIs	https://doi.org/10.1111/ina.12401
Publication status	Published - 2017 Nov

Bibliographical note

Funding Information:
National Program on Key Research Project of China, Grant/Award Number: 2016YFC0207000; Fundamental Research Funds for the Central Universities, Grant/ Award Number: 16ykzd02; the Guangdong Province Natural Science Foundation, Grant/ Award Number: 2014A050503027.

Funding Information:
This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the Guangdong Province Natural Science Foundation (No. 2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group.

Funding Information:
This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the GuangdongProvinceNaturalScienceFoundation(No.2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group.

Publisher Copyright:
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

All Science Journal Classification (ASJC) codes

Environmental Engineering
Building and Construction
Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/ina.12401

Cite this

@article{efa6ce2a571a46d0ae3bf3731218593c,

title = "Pre-natal and post-natal exposure to pet ownership and lung function in children: The Seven Northeastern Cities Study",

abstract = "To evaluate the association between pre-natal and post-natal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), and peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations were collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1.28; 95% confidence interval [CI]: 1.01, 1.63). For current pet exposure, the increased odds of lung function impairment ranged from 35% (aOR=1.35; 95%CI: 1.12, 1.62) for FVC<85% predicted to 57% (aOR=1.57; 95%CI: 1.29, 1.93) for FEV1<85% predicted. The in utero exposure was not related to lung function impairment. Compared with other pets, higher odds were observed among children with dogs. When stratified by gender, girls with current pet exposure were more likely to have lung function impairment than boys. It implies self-reported exposures to pets were negatively associated with lung function among the children under study.",

author = "Hu, {L. W.} and Z. Qian and Dharmage, {S. C.} and E. Liu and Howard, {S. W.} and Vaughn, {M. G.} and J. Perret and Lodge, {C. C.} and Zeng, {X. W.} and Yang, {B. Y.} and Xu, {S. L.} and C. Zhang and Dong, {G. H.}",

note = "Funding Information: National Program on Key Research Project of China, Grant/Award Number: 2016YFC0207000; Fundamental Research Funds for the Central Universities, Grant/ Award Number: 16ykzd02; the Guangdong Province Natural Science Foundation, Grant/ Award Number: 2014A050503027. Funding Information: This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the Guangdong Province Natural Science Foundation (No. 2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group. Funding Information: This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the GuangdongProvinceNaturalScienceFoundation(No.2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group. Publisher Copyright: {\textcopyright} 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd",

year = "2017",

month = nov,

doi = "10.1111/ina.12401",

language = "English",

volume = "27",

pages = "1177--1189",

journal = "Indoor Air",

issn = "0905-6947",

publisher = "Blackwell Munksgaard",

number = "6",

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TY - JOUR

T1 - Pre-natal and post-natal exposure to pet ownership and lung function in children

T2 - The Seven Northeastern Cities Study

AU - Hu, L. W.

AU - Qian, Z.

AU - Dharmage, S. C.

AU - Liu, E.

AU - Howard, S. W.

AU - Vaughn, M. G.

AU - Perret, J.

AU - Lodge, C. C.

AU - Zeng, X. W.

AU - Yang, B. Y.

AU - Xu, S. L.

AU - Zhang, C.

AU - Dong, G. H.

N1 - Funding Information: National Program on Key Research Project of China, Grant/Award Number: 2016YFC0207000; Fundamental Research Funds for the Central Universities, Grant/ Award Number: 16ykzd02; the Guangdong Province Natural Science Foundation, Grant/ Award Number: 2014A050503027. Funding Information: This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the Guangdong Province Natural Science Foundation (No. 2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group. Funding Information: This work was supported by Grants from the National Program on Key Research Project of China (No. 2016YFC0207000), the Fundamental Research Funds for the Central Universities (No. 16ykzd02), and the GuangdongProvinceNaturalScienceFoundation(No.2014A050503027). The participating families are gratefully acknowledged for their collaboration. We also thank the SNEC study group. Publisher Copyright: © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

PY - 2017/11

Y1 - 2017/11

N2 - To evaluate the association between pre-natal and post-natal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), and peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations were collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1.28; 95% confidence interval [CI]: 1.01, 1.63). For current pet exposure, the increased odds of lung function impairment ranged from 35% (aOR=1.35; 95%CI: 1.12, 1.62) for FVC<85% predicted to 57% (aOR=1.57; 95%CI: 1.29, 1.93) for FEV1<85% predicted. The in utero exposure was not related to lung function impairment. Compared with other pets, higher odds were observed among children with dogs. When stratified by gender, girls with current pet exposure were more likely to have lung function impairment than boys. It implies self-reported exposures to pets were negatively associated with lung function among the children under study.

AB - To evaluate the association between pre-natal and post-natal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), and peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations were collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1.28; 95% confidence interval [CI]: 1.01, 1.63). For current pet exposure, the increased odds of lung function impairment ranged from 35% (aOR=1.35; 95%CI: 1.12, 1.62) for FVC<85% predicted to 57% (aOR=1.57; 95%CI: 1.29, 1.93) for FEV1<85% predicted. The in utero exposure was not related to lung function impairment. Compared with other pets, higher odds were observed among children with dogs. When stratified by gender, girls with current pet exposure were more likely to have lung function impairment than boys. It implies self-reported exposures to pets were negatively associated with lung function among the children under study.

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Pre-natal and post-natal exposure to pet ownership and lung function in children: The Seven Northeastern Cities Study

Abstract

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UN SDGs

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