Positional relationship of superior and inferior labial artery by ultrasonography image analysis for safe lip augmentation procedures

Kyu Lim Lee, Hyung Jin Lee, Kwan Hyun Youn, Hee Jin Kim

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11 Citations (Scopus)


The aim of this study was to use ultrasonography to determine the locations and distributions of the superior labial artery (SLA) and the inferior labial artery (ILA) relative to the vermilion border (VB). Sixty healthy Korean volunteers (35 males, 25 females; age, 21–36 years) were investigated using ultrasonography. The participants had not received any noninvasive treatment or surgical procedure in the facial regions during the previous 6 months. Based on the VB, the overall thicknesses of the upper and lower lips were 9.4 ± 0.4 mm (mean ± SD) and 10.9 ± 0.7 mm, respectively. In most cases, the labial arteries were located in the wet mucosal layer on both the upper (35–57%) and lower lips (28–55%), respectively. In the upper lip, the SLA was in the intramuscular layer in 20–45% of cases, making it the second most common type. At some of the measuring points, the SLA was observed more often in the intramuscular layer than in the wet mucosal layer. In the lower lip, the ILA was also located in the dry mucosa (5–27%). The dry–wet mucosal junction is unclear in the lip area, and the ILA was commonly observed at the dry–wet mucosal junction. The arterial depth was 5.3 ± 0.3 mm in the upper lip and 4.2 ± 0.4 mm in the lower lip. The SLA and ILA are evenly distributed over all parts of the oral mucosa. Injection procedures for lip augmentation should therefore use very superficial approaches. Clin. Anat. 33:158–164, 2020.

Original languageEnglish
Pages (from-to)158-164
Number of pages7
JournalClinical Anatomy
Issue number2
Publication statusPublished - 2020 Mar 1

Bibliographical note

Funding Information:
The authors thank Hwi-Eun Hur (BA) from Davidson College for her revision of this manuscript. We also thank Su-Hyun Chae (MFA) from the National Cancer Center and Woo-Hyun Cho (MFA) from the Ajou University Medical Center for producing the figure materials. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (NRF-2017R1A2B4003781).

Publisher Copyright:
© 2019 Wiley Periodicals, Inc.

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Histology


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