Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan

Kwan Soo Ko; Tomomi Kuwahara; Kyungwon Lee; Yoon Hoh Kook

doi:10.1016/j.diagmicrobio.2009.03.008

Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan

Kwan Soo Ko, Tomomi Kuwahara, Kyungwon Lee, Yoon Hoh Kook

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi⁺ group from the cfi^- group. Combined sequences of the 60 division I isolates (cfi^-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.

Original language	English
Pages (from-to)	340-343
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	64
Issue number	3
DOIs	https://doi.org/10.1016/j.diagmicrobio.2009.03.008
Publication status	Published - 2009 Jul

Bibliographical note

Funding Information:
This work was supported in part by the BK21 Project for Medicine, Dentistry, and Pharmacy in Seoul National University, Seoul, South Korea.

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diagmicrobio.2009.03.008

Cite this

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title = "Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan",

abstract = "Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi+ group from the cfi- group. Combined sequences of the 60 division I isolates (cfi-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.",

author = "Ko, {Kwan Soo} and Tomomi Kuwahara and Kyungwon Lee and Kook, {Yoon Hoh}",

note = "Funding Information: This work was supported in part by the BK21 Project for Medicine, Dentistry, and Pharmacy in Seoul National University, Seoul, South Korea.",

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AU - Ko, Kwan Soo

AU - Kuwahara, Tomomi

AU - Lee, Kyungwon

AU - Kook, Yoon Hoh

N1 - Funding Information: This work was supported in part by the BK21 Project for Medicine, Dentistry, and Pharmacy in Seoul National University, Seoul, South Korea.

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N2 - Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi+ group from the cfi- group. Combined sequences of the 60 division I isolates (cfi-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.

AB - Sequences for rpoB, gyrB, pdiA, and ompA were determined from 63 Bacteroides fragilis isolates, which were from Korea and Japan and include 4 reference strains. All 4 gene sequences supported clear separation of the cfi+ group from the cfi- group. Combined sequences of the 60 division I isolates (cfi-) produced 45 different clones. Apparent discordance of gene trees, index of association, maximum likelihood test, and homoplasy ratio all supported a high frequency of recombination. There was no association between the presence of virulence-related genes and phylogenetic clustering in any gene tree.

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Population structure and distribution of virulence-related genes of Bacteroides fragilis isolates from Korea and Japan

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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