Polypoidal choroidal vasculopathy in Korean patients with large submacular hemorrhage

Jin Sook Yoon, Jonghyun Lee, Sung Chul Lee, Hyoung Jun Koh, Sung Soo Kim, Oh Woong Kwon

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Purpose: To determine and compare the clinical characteristics, visual prognosis and treatment of hemorrhagic polypoidal choroidal vasculopathy (HPCV) with those of hemorrhagic choroidal neovascularization (HCNV) due to age-related macular degeneration (ARMD). Materials and Methods: Retrospective analysis of 44 consecutive eyes with a submacular hemorrhage comprising more than 50% of the neovascular lesion. Patients were diagnosed as having HPCV or HCNV on the basis of indocyanine green angiography. Results: Of the 44 eyes with submacular hemorrhage, 26 were classified as HPCV and 18 as HCNV. The baseline patient characteristics were similar for both groups. At the final follow-up the HPCV group had 17 eyes showing visual improvement, four showing maintained vision, and five showing visual deterioration. In contrast, the HCNV group had four eyes showing visual improvement, one showing maintained vision, and 13 showing visual deterioration. Visual acuity of < 0.1 at follow-up was found in 7 (27 %) of HPCV eyes and 10 (56%) of HCNV eyes. PDT was performed in 15 HPCV eyes, of which 13 (87%) showed improvement or no change in visual acuity, while only 2 (22%) of the 9 HCNV eyes responded similarly after PDT. Eyes treated with PDT did not have better outcomes compared to eyes that underwent other types of treatment (Fisher's exact test, p > 0.05). Conclusion: PCV accounts for the largest proportion of submacular hemorrhage in Koreans. PCV showed a better visual prognosis than CNV.

Original languageEnglish
Pages (from-to)225-232
Number of pages8
JournalYonsei medical journal
Issue number2
Publication statusPublished - 2007 Apr

All Science Journal Classification (ASJC) codes

  • General Medicine


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